Literature DB >> 36203711

Conception of Saviour Siblings: Religious Views in Malaysia.

Chee Ying Kuek1, Sharon Kaur A/P Gurmukh Singh2.   

Abstract

The advancement of human reproductive technology has made it possible for parents with a child affected by a haematological disorder to select and bring into being, a prospective child who can act as a matched stem cell donor. This can be done through the use of preimplantation genetic diagnosis (PGD) coupled with human leukocyte antigen (HLA) typing (PGD-HLA typing), or HLA tying as a standalone procedure, where a healthy embryo, which is an HLA match to the existing sick sibling, is chosen for implantation. The creation of such a sibling (saviour sibling) is normally taken as a last resort when there is no related or unrelated matched donor. While the conception of a saviour sibling may serve as a reliable and realistic treatment option for the ailing child, it also poses new moral questions that challenge a religiously pluralistic society such as Malaysia. The use of PGD-HLA typing may be controversial as it involves creating a life to save a life, selection of compatible human embryos and destruction of the unselected embryos. At present, there is no legal framework regulating the conception of saviour siblings. The development of ethically sound and appropriate local laws and policies should consider the views of religious communities, especially when it involves a controversial subject such as the conception of saviour siblings. This article seeks to explore the perceptions of religious scholars and representatives of the major religions professed and practised in Malaysia, namely Islam, Buddhism, Christianity and Hinduism, through qualitative interviews. © National University of Singapore and Springer Nature Singapore Pte Ltd. 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Entities:  

Keywords:  HLA typing; Haematopoietic stem cell transplantation; Preimplantation genetic diagnosis; Religion; Reproductive Ethics; Saviour sibling

Year:  2022        PMID: 36203711      PMCID: PMC9530092          DOI: 10.1007/s41649-022-00216-3

Source DB:  PubMed          Journal:  Asian Bioeth Rev        ISSN: 1793-9453


  9 in total

1.  The human embryo in the Christian tradition: a reconsideration.

Authors:  D A Jones
Journal:  J Med Ethics       Date:  2005-12       Impact factor: 2.903

Review 2.  Making regulations and drawing up legislation in Islamic countries under conditions of uncertainty, with special reference to embryonic stem cell research.

Authors:  S Aksoy
Journal:  J Med Ethics       Date:  2005-07       Impact factor: 2.903

3.  Religion and bioethics: toward an expanded understanding.

Authors:  Howard Brody; Arlene Macdonald
Journal:  Theor Med Bioeth       Date:  2013-04

4.  Religious belief, perceptions of human suffering, and support for reproductive genetic technology.

Authors:  John H Evans
Journal:  J Health Polit Policy Law       Date:  2006-12       Impact factor: 2.265

5.  The moral status of the human embryo: a tradition recalled.

Authors:  G R Dunstan
Journal:  J Med Ethics       Date:  1984-03       Impact factor: 2.903

Review 6.  Islamic ethical framework for research into and prevention of genetic diseases.

Authors:  Aida I Al Aqeel
Journal:  Nat Genet       Date:  2007-10-22       Impact factor: 38.330

7.  Religious Scholars' Attitudes and Views on Ethical Issues Pertaining to Pre-Implantation Genetic Diagnosis (PGD) in Malaysia.

Authors:  A Olesen; S N Nor; L Amin
Journal:  J Bioeth Inq       Date:  2016-06-30       Impact factor: 1.352

8.  Conception of Saviour Siblings: Ethical Perceptions of Selected Stakeholders in Malaysia.

Authors:  Chee Ying Kuek; Sharon Kaur A/P Gurmukh Singh; Pek San Tay
Journal:  Asian Bioeth Rev       Date:  2021-03-17

9.  Controversies and considerations regarding the termination of pregnancy for foetal anomalies in Islam.

Authors:  Abdulrahman Al-Matary; Jaffar Ali
Journal:  BMC Med Ethics       Date:  2014-02-05       Impact factor: 2.652

  9 in total

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