| Literature DB >> 3619652 |
R Joeres, H Klinker, H Huesler, J Epping, G Hofstetter, D Drost, H Reuss, W Zilly, E Richter.
Abstract
Liver functions in patients with liver disease can be estimated by caffeine clearance. Our data, however, demonstrate the additional influence of factors other than liver disease on the caffeine test. Smoking enhances caffeine clearance in both healthy volunteers and patients with severe hepatic disorders, whereas co-medication with mexiletine strongly inhibits caffeine elimination.Entities:
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Year: 1987 PMID： 3619652 DOI： 10.1007/bf00296957
Source DB: PubMed Journal: Arch Toxicol ISSN： 0340-5761 Impact factor: 5.153