Literature DB >> 36185397

650 GHz imaging as alignment verification for millimeter wave corneal reflectometry.

Yong Hu1, Mariangela Baggio2, Shahab Dabironezare3, Aleksi Tamminen2, Brandon Toy4, Juha Ala-Laurinaho2, Elliott Brown5, Nuria Llombart3, Sophie X Deng6, Vincent Wallace7, Zachary D Taylor2.   

Abstract

A system concept for online alignment verification of millimeter-wave, corneal reflectometry is presented. The system utilizes beam scanning to generate magnitude-only reflectivity maps of the cornea at 650 GHz and compares these images to a precomputed/measured template map to confirm/reject sufficient alignment. A system utilizing 5 off-axis parabolic mirrors, a thin film beam splitter, and 2-axis galvanometric mirror was designed, simulated, and evaluated with geometric and physical optics. Simulation results informed the construction of a demonstrator system which was tested with a reference reflector. Similarity metrics computed with the aligned template and 26 misaligned positions, distributed on a 0.5 mm x 0.5 mm x 0.5 mm mesh, demonstrated sufficient misalignment detection sensitivity in 23 out of 26 positions. The results show that positional accuracy on the order of 0.5 mm is possible using 0.462 mm wavelength radiation due to the perturbation of coupling efficiency via beam distortion and beam walk-off.

Entities:  

Keywords:  Biological and medical imaging; THz imaging of cornea; clinical instruments; medical diagnostics

Year:  2022        PMID: 36185397      PMCID: PMC9518788          DOI: 10.1109/tthz.2021.3140199

Source DB:  PubMed          Journal:  IEEE Trans Terahertz Sci Technol        ISSN: 2156-342X            Impact factor:   3.468


  16 in total

1.  Graft rejection following descemet stripping automated endothelial keratoplasty: features, risk factors, and outcomes.

Authors:  Elaine I Wu; David C Ritterband; Guopei Yu; Rebecca A Shields; John A Seedor
Journal:  Am J Ophthalmol       Date:  2012-01-20       Impact factor: 5.258

2.  Tear film measurement by optical reflectometry technique.

Authors:  Hui Lu; Michael R Wang; Jianhua Wang; Meixiao Shen
Journal:  J Biomed Opt       Date:  2014-02       Impact factor: 3.170

Review 3.  Descemet Membrane Endothelial Keratoplasty: Safety and Outcomes: A Report by the American Academy of Ophthalmology.

Authors:  Sophie X Deng; W Barry Lee; Kristin M Hammersmith; Anthony N Kuo; Jennifer Y Li; Joanne F Shen; Mitchell P Weikert; Roni M Shtein
Journal:  Ophthalmology       Date:  2017-09-15       Impact factor: 12.079

4.  THz imaging system for in vivo human cornea.

Authors:  Shijun Sung; Skyler Selvin; Neha Bajwa; Somporn Chantra; Bryan Nowroozi; James Garritano; Jacob Goell; Alex Li; Sophie X Deng; Elliott Brown; Warren S Grundfest; Zachary D Taylor
Journal:  IEEE Trans Terahertz Sci Technol       Date:  2017-12-07       Impact factor: 3.274

5.  THz and mm-Wave Sensing of Corneal Tissue Water Content: In Vivo Sensing and Imaging Results.

Authors:  Zachary D Taylor; James Garritano; Shijun Sung; Neha Bajwa; David B Bennett; Bryan Nowroozi; Priyamvada Tewari; James W Sayre; Jean-Pierre Hubschman; Sophie X Deng; Elliott R Brown; Warren S Grundfest
Journal:  IEEE Trans Terahertz Sci Technol       Date:  2015-03       Impact factor: 3.274

6.  In vivo sensing of rabbit cornea by terahertz technology.

Authors:  Lin Ke; Nan Zhang; Qing Yang Steve Wu; Sergey Gorelik; Ali Abdelaziem; Zheng Liu; Erica Pei Wen Teo; Jodhbir S Mehta; Yu-Chi Liu
Journal:  J Biophotonics       Date:  2021-06-09       Impact factor: 3.207

7.  THz and mm-Wave Sensing of Corneal Tissue Water Content: Electromagnetic Modeling and Analysis.

Authors:  Zachary D Taylor; James Garritano; Shijun Sung; Neha Bajwa; David B Bennett; Bryan Nowroozi; Priyamvada Tewari; James Sayre; Jean-Pierre Hubschman; Sophie Deng; Elliott R Brown; Warren S Grundfest
Journal:  IEEE Trans Terahertz Sci Technol       Date:  2015-03       Impact factor: 3.274

8.  Corneal transplant rejection rate and severity after endothelial keratoplasty.

Authors:  Bruce D S Allan; Mark A Terry; Francis W Price; Marianne O Price; Neil B Griffin; Margareta Claesson
Journal:  Cornea       Date:  2007-10       Impact factor: 2.651

9.  Optical System Design for Noncontact, Normal Incidence, THz Imaging of in vivo Human Cornea.

Authors:  Shijun Sung; Shahab Dabironezare; Nuria Llombart; Skyler Selvin; Neha Bajwa; Somporn Chantra; Bryan Nowroozi; James Garritano; Jacob Goell; Alex Li; Sophie X Deng; Elliott Brown; Warren S Grundfest; Zachary D Taylor
Journal:  IEEE Trans Terahertz Sci Technol       Date:  2017-11-22       Impact factor: 3.274

10.  Robust automatic segmentation of corneal layer boundaries in SDOCT images using graph theory and dynamic programming.

Authors:  Francesco Larocca; Stephanie J Chiu; Ryan P McNabb; Anthony N Kuo; Joseph A Izatt; Sina Farsiu
Journal:  Biomed Opt Express       Date:  2011-05-12       Impact factor: 3.732

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