Literature DB >> 3618112

CSF neopterin as marker of disease activity in multiple sclerosis.

S Fredrikson, H Link, P Eneroth.   

Abstract

Levels of neopterin, a factor known to be released from macrophages and monocytes at increased rates in cellular immune reactions, were higher in cerebrospinal fluid (CSF) in 10 of 12 patients with multiple sclerosis (MS) during exacerbations in comparison with remissions. This significant elevation in CSF during exacerbations was not reflected in serum. These results indicate that determination of neopterin in CSF may be a useful marker of disease activity in MS.

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Year:  1987        PMID： 3618112     DOI： 10.1111/j.1600-0404.1987.tb05458.x

Source DB:  PubMed          Journal:  Acta Neurol Scand        ISSN： 0001-6314            Impact factor:   3.209


  17 in total

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3.  Serum Immune System Biomarkers Neopterin and Interleukin-10 Are Strongly Related to Tryptophan Metabolism in Healthy Young Adults.

Authors:  Oana M Deac; James L Mills; Clair M Gardiner; Barry Shane; Louise Quinn; Øivind Midttun; Adrian McCann; Klaus Meyer; Per M Ueland; Ruzong Fan; Zhaohui Lu; Lawrence C Brody; Anne M Molloy
Journal:  J Nutr       Date:  2016-08-03       Impact factor: 4.798

4.  Expression of urokinase plasminogen activator receptor on monocytes from patients with relapsing-remitting multiple sclerosis: effect of glatiramer acetate (copolymer 1).

Authors:  R Balabanov; D Lisak; T Beaumont; R P Lisak; P Dore-Duffy
Journal:  Clin Diagn Lab Immunol       Date:  2001-11

Review 5.  Cerebrospinal fluid.

Authors:  E J Thompson
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-10       Impact factor: 10.154

6.  Evidence for increased nitric oxide production in multiple sclerosis.

Authors:  A W Johnson; J M Land; E J Thompson; J P Bolaños; J B Clark; S J Heales
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-01       Impact factor: 10.154

7.  Cerebrospinal fluid and serum neopterin levels in patients with Lyme neuroborreliosis.

Authors:  L Dotevall; D Fuchs; G Reibnegger; H Wachter; L Hagberg
Journal:  Infection       Date:  1990 Jul-Aug       Impact factor: 3.553

8.  Neopterin in tuberculous and neoplastic pleural fluids.

Authors:  M F Baganha; A Mota-Pinto; M A Pêgo; M A Marques; M A Rosa; A J Cordeiro
Journal:  Lung       Date:  1992       Impact factor: 2.584

9.  Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission.

Authors:  C E Shaw; P R Dunbar; H A Macaulay; T J Neale
Journal:  J Neurol       Date:  1995-01       Impact factor: 4.849

10.  Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy.

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