Literature DB >> 2210852

Cerebrospinal fluid and serum neopterin levels in patients with Lyme neuroborreliosis.

L Dotevall1, D Fuchs, G Reibnegger, H Wachter, L Hagberg.   

Abstract

Elevated (greater than 3.0 nmol/l) cerebrospinal fluid neopterin concentrations were observed in 20 of 21 patients with Lyme neuroborreliosis compared with three of 11 control patients with headache, back pain or psychoneurotic disorders. Neopterin concentrations were correlated to mononuclear cell counts and protein concentrations in the cerebrospinal fluid (CSF). Following antibiotic treatment, CSF neopterin levels decreased. Serum neopterin levels were not significantly raised in patients with neuroborreliosis when compared to control subjects. Neopterin levels as well as cell count and protein concentration in the CSF are valuable inflammation markers of disease activity in Lyme neuroborreliosis.

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Year:  1990        PMID： 2210852     DOI： 10.1007/bf01643387

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  17 in total

1.  Cytological and immunoglobulin findings in cerebrospinal fluid of symptomatic and asymptomatic human immunodeficiency virus (HIV) seropositive patients.

Authors:  L Hagberg; A Forsman; G Norkrans; E Rybo; L Svennerholm
Journal:  Infection       Date:  1988       Impact factor: 3.553

2.  Specific immune responses in Lyme borreliosis. Characterization of T cell and B cell responses to Borrelia burgdorferi.

Authors:  R J Dattwyler; D J Volkman; J J Halperin; B J Luft; J Thomas; M G Golightly
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

3.  Determination of neopterin in serum and urine.

Authors:  E R Werner; A Bichler; G Daxenbichler; D Fuchs; L C Fuith; A Hausen; H Hetzel; G Reibnegger; H Wachter
Journal:  Clin Chem       Date:  1987-01       Impact factor: 8.327

4.  CSF neopterin as marker of disease activity in multiple sclerosis.

Authors:  S Fredrikson; H Link; P Eneroth
Journal:  Acta Neurol Scand       Date:  1987-05       Impact factor: 3.209

5.  Lyme disease spirochetes induce human and murine interleukin 1 production.

Authors:  G S Habicht; G Beck; J L Benach; J L Coleman; K D Leichtling
Journal:  J Immunol       Date:  1985-05       Impact factor: 5.422

6.  Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1.

Authors:  D Fuchs; F Chiodi; J Albert; B Asjö; L Hagberg; A Hausen; G Norkrans; G Reibnegger; E R Werner; H Wachter
Journal:  AIDS       Date:  1989-05       Impact factor: 4.177

7.  Intrathecal production of neopterin in aseptic meningo-encephalitis and multiple sclerosis.

Authors:  S Fredrikson; P Eneroth; H Link
Journal:  Clin Exp Immunol       Date:  1987-01       Impact factor: 4.330

Review 8.  Lyme disease.

Authors:  A C Steere
Journal:  N Engl J Med       Date:  1989-08-31       Impact factor: 91.245

9.  Diagnosis of spirochetal meningitis by enzyme-linked immunosorbent assay and indirect immunofluorescence assay in serum and cerebrospinal fluid.

Authors:  G T Stiernstedt; M Granström; B Hederstedt; B Sköldenberg
Journal:  J Clin Microbiol       Date:  1985-05       Impact factor: 5.948

10.  Tick-borne meningopolyneuritis (Garin-Bujadoux, Bannwarth).

Authors:  R Ackermann; P Hörstrup; R Schmidt
Journal:  Yale J Biol Med       Date:  1984 Jul-Aug
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  5 in total

1.  Increased cerebrospinal fluid levels of glial fibrillary acidic protein (GFAp) in Lyme neuroborreliosis.

Authors:  L Dotevall; L E Rosengren; L Hagberg
Journal:  Infection       Date:  1996 Mar-Apr       Impact factor: 3.553

2.  CSF neopterin level as a diagnostic marker in primary central nervous system lymphoma.

Authors:  Aurélien Viaccoz; François Ducray; Yannick Tholance; Gleicy Keli Barcelos; Laure Thomas-Maisonneuve; Hervé Ghesquières; David Meyronet; Isabelle Quadrio; Stéphanie Cartalat-Carel; Guy Louis-Tisserand; Emmanuel Jouanneau; Jacques Guyotat; Jérôme Honnorat; Armand Perret-Liaudet
Journal:  Neuro Oncol       Date:  2015-05-25       Impact factor: 12.300

3.  Expansion of neopterin and beta 2-microglobulin in cerebrospinal fluid reaches maximum levels early and late in the course of human immunodeficiency virus infection.

Authors:  J R Bogner; B Junge-Hülsing; U Kronawitter; I Sadri; A Matuschke; F D Goebel
Journal:  Clin Investig       Date:  1992-08

4.  Lyme borreliosis of central nervous system (CNS) in children: a diagnostic challenge.

Authors:  M M Millner; R R Müllegger; K D Spork; G Stanek
Journal:  Infection       Date:  1991 Jul-Aug       Impact factor: 3.553

5.  Cerebrospinal fluid HIV-1 RNA, intrathecal immunoactivation, and drug concentrations after treatment with a combination of saquinavir, nelfinavir, and two nucleoside analogues: the M61022 study.

Authors:  Aylin Yilmaz; Dietmar Fuchs; Lars Hagberg; Ulrika Nillroth; Lars Ståhle; Jan-Olof Svensson; Magnus Gisslén
Journal:  BMC Infect Dis       Date:  2006-03-27       Impact factor: 3.090
  5 in total

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