| Literature DB >> 36180685 |
Mariette Matondo1, Guillaume Dumas2,3, Erik Maronde4.
Abstract
The human pineal gland regulates the day-night dynamics of multiple physiological processes, especially through the secretion of melatonin. Recently, using mass spectrometry-based proteomics and dedicated analysis tools, we have identified regulated proteins and signaling pathways that differ between day and night and/or between control and autistic pineal glands. This large-scale proteomic approach is the method of choice to study proteins in a biological system globally. This chapter proposes a protocol for large-scale analysis of the pineal gland proteome.Entities:
Keywords: Autism; Human; Mass spectrometry; Pineal gland; Protein
Mesh:
Substances:
Year: 2022 PMID: 36180685 DOI: 10.1007/978-1-0716-2593-4_16
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745