Literature DB >> 36131149

Artificial intelligence foundation for therapeutic science.

Kexin Huang1,2, Tianfan Fu3, Wenhao Gao4, Yue Zhao5, Yusuf Roohani6, Jure Leskovec2, Connor W Coley4, Cao Xiao7, Jimeng Sun8, Marinka Zitnik9,10,11.   

Abstract

Entities:  

Year:  2022        PMID： 36131149      PMCID： PMC9529840          DOI： 10.1038/s41589-022-01131-2

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   16.174


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  21 in total

Review 1.  Impact of high-throughput screening in biomedical research.

Authors:  Ricardo Macarron; Martyn N Banks; Dejan Bojanic; David J Burns; Dragan A Cirovic; Tina Garyantes; Darren V S Green; Robert P Hertzberg; William P Janzen; Jeff W Paslay; Ulrich Schopfer; G Sitta Sittampalam
Journal:  Nat Rev Drug Discov       Date:  2011-03       Impact factor: 84.694

Review 2.  Deep learning.

Authors:  Yann LeCun; Yoshua Bengio; Geoffrey Hinton
Journal:  Nature       Date:  2015-05-28       Impact factor: 49.962

3.  GuacaMol: Benchmarking Models for de Novo Molecular Design.

Authors:  Nathan Brown; Marco Fiscato; Marwin H S Segler; Alain C Vaucher
Journal:  J Chem Inf Model       Date:  2019-03-19       Impact factor: 4.956

Review 4.  Inverse molecular design using machine learning: Generative models for matter engineering.

Authors:  Benjamin Sanchez-Lengeling; Alán Aspuru-Guzik
Journal:  Science       Date:  2018-07-26       Impact factor: 47.728

5.  The Synthesizability of Molecules Proposed by Generative Models.

Authors:  Wenhao Gao; Connor W Coley
Journal:  J Chem Inf Model       Date:  2020-04-17       Impact factor: 4.956

6.  Assessing the impact of generative AI on medicinal chemistry.

Authors:  W Patrick Walters; Mark Murcko
Journal:  Nat Biotechnol       Date:  2020-02       Impact factor: 54.908

Review 7.  Drug repurposing: progress, challenges and recommendations.

Authors:  Sudeep Pushpakom; Francesco Iorio; Patrick A Eyers; K Jane Escott; Shirley Hopper; Andrew Wells; Andrew Doig; Tim Guilliams; Joanna Latimer; Christine McNamee; Alan Norris; Philippe Sanseau; David Cavalla; Munir Pirmohamed
Journal:  Nat Rev Drug Discov       Date:  2018-10-12       Impact factor: 84.694

8.  DeepDTA: deep drug-target binding affinity prediction.

Authors:  Hakime Öztürk; Arzucan Özgür; Elif Ozkirimli
Journal:  Bioinformatics       Date:  2018-09-01       Impact factor: 6.937

9.  Highly accurate protein structure prediction with AlphaFold.

Authors:  John Jumper; Richard Evans; Alexander Pritzel; Tim Green; Michael Figurnov; Olaf Ronneberger; Kathryn Tunyasuvunakool; Russ Bates; Augustin Žídek; Anna Potapenko; Alex Bridgland; Clemens Meyer; Simon A A Kohl; Andrew J Ballard; Andrew Cowie; Bernardino Romera-Paredes; Stanislav Nikolov; Rishub Jain; Demis Hassabis; Jonas Adler; Trevor Back; Stig Petersen; David Reiman; Ellen Clancy; Michal Zielinski; Martin Steinegger; Michalina Pacholska; Tamas Berghammer; Sebastian Bodenstein; David Silver; Oriol Vinyals; Andrew W Senior; Koray Kavukcuoglu; Pushmeet Kohli
Journal:  Nature       Date:  2021-07-15       Impact factor: 49.962
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