Literature DB >> 36131039

The controversial embryo tests that promise a better baby.

Max Kozlov.   

Abstract

Entities:  

Keywords:  Ethics; Genomics; Health care

Mesh：

Year:  2022        PMID： 36131039     DOI： 10.1038/d41586-022-02961-9

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


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  4 in total

1.  Screening Human Embryos for Polygenic Traits Has Limited Utility.

Authors:  Ehud Karavani; Or Zuk; Danny Zeevi; Nir Barzilai; Nikos C Stefanis; Alex Hatzimanolis; Nikolaos Smyrnis; Dimitrios Avramopoulos; Leonid Kruglyak; Gil Atzmon; Max Lam; Todd Lencz; Shai Carmi
Journal:  Cell       Date:  2019-11-21       Impact factor: 41.582

2.  Problems with Using Polygenic Scores to Select Embryos.

Authors:  Patrick Turley; Michelle N Meyer; Nancy Wang; David Cesarini; Evelynn Hammonds; Alicia R Martin; Benjamin M Neale; Heidi L Rehm; Louise Wilkins-Haug; Daniel J Benjamin; Steven Hyman; David Laibson; Peter M Visscher
Journal:  N Engl J Med       Date:  2021-07-01       Impact factor: 91.245

3.  Whole-genome risk prediction of common diseases in human preimplantation embryos.

Authors:  Akash Kumar; Kate Im; Milena Banjevic; Pauline C Ng; Tate Tunstall; Geronimo Garcia; Luisa Galhardo; Jiayi Sun; Oren N Schaedel; Brynn Levy; Donna Hongo; Dusan Kijacic; Michelle Kiehl; Nam D Tran; Peter C Klatsky; Matthew Rabinowitz
Journal:  Nat Med       Date:  2022-03-21       Impact factor: 53.440

4.  Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations.

Authors:  Amit V Khera; Mark Chaffin; Krishna G Aragam; Mary E Haas; Carolina Roselli; Seung Hoan Choi; Pradeep Natarajan; Eric S Lander; Steven A Lubitz; Patrick T Ellinor; Sekar Kathiresan
Journal:  Nat Genet       Date:  2018-08-13       Impact factor: 38.330
  4 in total

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