Literature DB >> 36125607

Catalyst-free synthesis of acenaphthoindolopyrimidine derivatives.

Nahale Kakavand1, Mohammad Bayat2, Yadollah Bayat3.   

Abstract

A one pot three component reaction of acenaphthoquinone, barbituric acid/thiobarbituric acid/N,N-dimethyl barbituric acid and arylamines in ethanol for the synthesis of acenaphthoindolopyrimidine derivatives is reported. The reactions take place without a catalyst and gentle conditions. This method is facile and has some benefits such as, readily available starting materials, green solvent, catalyst-free, no column chromatographic purification and good to high yields.
© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.

Entities:  

Keywords:  Acenaphthoquinone; Arylamines; Barbituric acid; N,N-Dimethyl barbituric acid; Thiobarbituric acid

Year:  2022        PMID： 36125607     DOI： 10.1007/s11030-022-10531-4

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   3.364


  10 in total

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Journal:  Org Lett       Date:  2011-08-22       Impact factor: 6.005

8.  Synthesis and antioxidant activity of new tetraarylpyrroles.

Authors: 
Journal:  Eur J Med Chem       Date:  1999-11-01       Impact factor: 6.514

9.  A catalytic asymmetric isatin-involved Povarov reaction: diastereo- and enantioselective construction of spiro[indolin-3,2'-quinoline] scaffold.

Authors:  Feng Shi; Gui-Juan Xing; Ren-Yi Zhu; Wei Tan; Shujiang Tu
Journal:  Org Lett       Date:  2012-12-14       Impact factor: 6.005

10.  Organocatalytic Asymmetric Synthesis of Indole-Based Chiral Heterocycles: Strategies, Reactions, and Outreach.

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Journal:  Acc Chem Res       Date:  2019-12-10       Impact factor: 22.384
  10 in total

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