Literature DB >> 23240812

A catalytic asymmetric isatin-involved Povarov reaction: diastereo- and enantioselective construction of spiro[indolin-3,2'-quinoline] scaffold.

Feng Shi1, Gui-Juan Xing, Ren-Yi Zhu, Wei Tan, Shujiang Tu.   

Abstract

The first catalytic asymmetric isatin-involved Povarov reaction has been established. This method provides an unprecedented approach to access the enantioenriched spiro[indolin-3,2'-quinoline] scaffold with concomitant creation of two quaternary stereogenic centers in high yields and excellent stereoselectivities (all >99:1 dr's, up to 97% ee).

Entities:  

Year:  2012        PMID： 23240812     DOI： 10.1021/ol303154k

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  7 in total

1.  A synthesis of fused acenaphthopyrrolizines via the 1,3-dipolar cycloaddition reaction of azomethine ylides with acetylenic esters.

Authors:  Issa Yavari; Leila Baoosi; Mohammad R Halvagar
Journal:  Mol Divers       Date:  2017-01-13       Impact factor: 2.943

2.  An efficient three-component synthesis of highly functionalized tetrahydroacenaphtho[1,2-b]indolone derivatives catalyzed by L-proline.

Authors:  Juan-Juan Zhang; Xian Feng; Xue-Cheng Liu; Zhi-Bin Huang; Da-Qing Shi
Journal:  Mol Divers       Date:  2014-08-24       Impact factor: 2.943

3.  Catalyst-free synthesis of acenaphthoindolopyrimidine derivatives.

Authors:  Nahale Kakavand; Mohammad Bayat; Yadollah Bayat
Journal:  Mol Divers       Date:  2022-09-20       Impact factor: 3.364

4.  Adaptation of a small-molecule hydrogen-bond donor catalyst to an enantioselective hetero-Diels-Alder reaction hypothesized for brevianamide biosynthesis.

Authors:  Daniel J Sprague; Benjamin M Nugent; Ryan A Yoder; Brandon A Vara; Jeffrey N Johnston
Journal:  Org Lett       Date:  2015-01-31       Impact factor: 6.005

Review 5.  The Cascade [1,5]-Hydride Shift/Intramolecular C(sp3)-H Activation: A Powerful Approach to the Construction of Spiro-Tetrahydroquinoline Skeleton.

Authors:  Hongmei Liu; Yunyun Quan; Long Xie; Xiang Li; Xin Xie
Journal:  Front Chem       Date:  2022-04-07       Impact factor: 5.545

6.  Synthesis of spiroimidazopyridineoxindole, spiropyridopyrimidineoxindole and spiropyridodiazepineoxindole derivatives based on heterocyclic ketene aminals via a four-component reaction.

Authors:  Fatemeh Rahimi; Mohammad Bayat; Hajar Hosseini
Journal:  RSC Adv       Date:  2019-05-24       Impact factor: 4.036

7.  Iodide/H₂O₂ Catalyzed Intramolecular Oxidative Amination for the Synthesis of 3,2'-Pyrrolidinyl Spirooxindoles.

Authors:  Yu-Ting Gao; Xiao-Yang Jin; Qi Liu; An-Di Liu; Liang Cheng; Dong Wang; Li Liu
Journal:  Molecules       Date:  2018-09-05       Impact factor: 4.411
  7 in total

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