| Literature DB >> 36124200 |
Konstadinos Sotiropulos1, Dimitrios Kourkoutas2, Diamantis Almaliotis3, Katherine Ploumidou4, Vasileios Karampatakis3.
Abstract
Stem cells are undifferentiated cells showcasing a remarkable capacity of self-replenishing and differentiating into mature cells. Their ability to proliferate connotes that a designated stem cell source is capable of generating an unrestricted number of mature cells. The ever-increasing comprehension of position, activity, and function of ocular stem cells has led to rapid progress and incessant improvement of possible procedures and therapies. A narrative review was conducted to summarize the current evidence on clinical trials and respective literature, regarding current evolution in the field of ocular regenerative medicine. We tried to ascertain the safety of experimental and clinical procedures, their effectiveness, and the ethical repercussion of their use. International Journal of Ophthalmology Press.Entities:
Keywords: cell-based therapies; hESC-derived retinal pigment epithelium; human induced pluripotent stem cells; limbal stem cells; olfactory mucosa mesenchymal stem cells; stem cells
Year: 2022 PMID: 36124200 PMCID: PMC9453397 DOI: 10.18240/ijo.2022.09.17
Source DB: PubMed Journal: Int J Ophthalmol ISSN: 2222-3959 Impact factor: 1.645