Literature DB >> 18295572

Stem cells and drug discovery: the beginning of a new era?

Lee L Rubin1.   

Abstract

Much of the attention focused on stem cells relates to their use in cell replacement therapy; however, stem cells may also transform the way in which therapeutics are discovered and validated.

Mesh:

Year:  2008        PMID: 18295572     DOI: 10.1016/j.cell.2008.02.010

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  57 in total

1.  Modeling and therapy of human liver diseases using induced pluripotent stem cells: how far have we come?

Authors:  Alejandro Soto-Gutierrez; Edgar Tafaleng; Victoria Kelly; Jayanta Roy-Chowdhury; Ira J Fox
Journal:  Hepatology       Date:  2011-02       Impact factor: 17.425

2.  Neuromuscular junction formation between human stem cell-derived motoneurons and human skeletal muscle in a defined system.

Authors:  Xiufang Guo; Mercedes Gonzalez; Maria Stancescu; Herman H Vandenburgh; James J Hickman
Journal:  Biomaterials       Date:  2011-09-23       Impact factor: 12.479

Review 3.  Human motor neuron generation from embryonic stem cells and induced pluripotent stem cells.

Authors:  M Nizzardo; C Simone; M Falcone; F Locatelli; G Riboldi; G P Comi; S Corti
Journal:  Cell Mol Life Sci       Date:  2010-07-29       Impact factor: 9.261

Review 4.  Embryonic and induced pluripotent stem cells as a model for liver disease.

Authors:  Hiroshi Yagi; Edgar Tafaleng; Masaki Nagaya; Marc C Hansel; Stephen C Strom; Ira J Fox; Alejandro Soto-Gutierrez
Journal:  Crit Rev Biomed Eng       Date:  2009

5.  Cardiovascular Stem Cells in Regenerative Medicine: Ready for Prime Time?

Authors:  Yuan-Hung Liu; Ravi Karra; Sean M Wu
Journal:  Drug Discov Today Ther Strateg       Date:  2008

6.  Embryonic Stem Cells as a Model for Cardiac Development and Disease.

Authors:  Todd Evans
Journal:  Drug Discov Today Dis Models       Date:  2008

7.  Stem cell platforms for regenerative medicine.

Authors:  Timothy J Nelson; Atta Behfar; Satsuki Yamada; Almudena Martinez-Fernandez; Andre Terzic
Journal:  Clin Transl Sci       Date:  2009-06       Impact factor: 4.689

Review 8.  Technical challenges in using human induced pluripotent stem cells to model disease.

Authors:  Krishanu Saha; Rudolf Jaenisch
Journal:  Cell Stem Cell       Date:  2009-12-04       Impact factor: 24.633

Review 9.  Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience.

Authors:  Jerome Mertens; Maria C Marchetto; Cedric Bardy; Fred H Gage
Journal:  Nat Rev Neurosci       Date:  2016-05-19       Impact factor: 34.870

Review 10.  Progress toward the clinical application of patient-specific pluripotent stem cells.

Authors:  Evangelos Kiskinis; Kevin Eggan
Journal:  J Clin Invest       Date:  2010-01       Impact factor: 14.808

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