AIM: To assess the reproducibility of macular perfusion parameters in non-proliferative diabetic retinopathy (NPDR) patients measured by different examiners and two different sweep modes of optical coherence tomography angiography (OCTA). METHODS: Ninety-eight (98 eyes) patients with NPDR were included in this study. All participates were performed three times using Cirrus OCTA with Angiography 3×3 mm2 and 6×6 mm2 sweep mode by two examiners. The macular foveal avascular zone (FAZ) and vessel density (VD) in the superficial retinal layer (SRL) were measured. The reproducibility of the measurements was evaluated with intraclass correlation coefficients (ICC) and coefficient of variation (CoV). RESULTS: The intra-mode ICCs of Angiography 3×3 mm2 and 6×6 mm2 sweep mode were 0.957 to 0.959 and 0.964 to 0.977, respectively; and the inter-mode ICCs were 0.962 to 0.970. The intra-examiner ICCs of macular perfusion parameters were >0.950; and the inter-examiner ICCs were 0.928 to 0.969. All CoVs were <1.0%. CONCLUSION: Cirrus OCTA can measure macular perfusion parameters in NPDR patients with excellent reproducibility. The measurements of FAZ and VD in the SRL determined by Angiography 3×3 mm2 and 6×6 mm2 sweep mode are highly consistent and both sweep modes are suitable for macular perfusion parameters measurement. International Journal of Ophthalmology Press.
AIM: To assess the reproducibility of macular perfusion parameters in non-proliferative diabetic retinopathy (NPDR) patients measured by different examiners and two different sweep modes of optical coherence tomography angiography (OCTA). METHODS: Ninety-eight (98 eyes) patients with NPDR were included in this study. All participates were performed three times using Cirrus OCTA with Angiography 3×3 mm2 and 6×6 mm2 sweep mode by two examiners. The macular foveal avascular zone (FAZ) and vessel density (VD) in the superficial retinal layer (SRL) were measured. The reproducibility of the measurements was evaluated with intraclass correlation coefficients (ICC) and coefficient of variation (CoV). RESULTS: The intra-mode ICCs of Angiography 3×3 mm2 and 6×6 mm2 sweep mode were 0.957 to 0.959 and 0.964 to 0.977, respectively; and the inter-mode ICCs were 0.962 to 0.970. The intra-examiner ICCs of macular perfusion parameters were >0.950; and the inter-examiner ICCs were 0.928 to 0.969. All CoVs were <1.0%. CONCLUSION: Cirrus OCTA can measure macular perfusion parameters in NPDR patients with excellent reproducibility. The measurements of FAZ and VD in the SRL determined by Angiography 3×3 mm2 and 6×6 mm2 sweep mode are highly consistent and both sweep modes are suitable for macular perfusion parameters measurement. International Journal of Ophthalmology Press.
Authors: Christian Enders; Franziska Baeuerle; Gabriele E Lang; Jens Dreyhaupt; Gerhard K Lang; Max Loidl; Jens Ulrich Werner Journal: Ophthalmologica Date: 2019-05-28 Impact factor: 3.250
Authors: Jie Xu; Wen Bin Wei; Ming Xia Yuan; Shen Yuan Yuan; Gang Wan; Yuan Yuan Zheng; Yi Bin Li; Shuang Wang; Liang Xu; Han Jing Fu; Liang Xiang Zhu; Xiang Lei Pu; Jian Dong Zhang; Xue Ping Du; Yu Lin Li; Yu Ji; Xiao Ning Gu; Yue Li; Su Fang Pan; Xue Li Cui; Wei Bai; Yu Jie Chen; Zi Min Wang; Qing Sheng Zhu; Ying Gao; De Yuan Liu; Yun Tao Ji; Ze Yang; Jost B Jonas Journal: Retina Date: 2012-02 Impact factor: 4.256
Authors: Rohit Varma; Neil M Bressler; Quan V Doan; Michelle Gleeson; Mark Danese; Julie K Bower; Elizabeth Selvin; Chantal Dolan; Jennifer Fine; Shoshana Colman; Adam Turpcu Journal: JAMA Ophthalmol Date: 2014-11 Impact factor: 7.389
Authors: Rodolfo Mastropasqua; Lisa Toto; Alessandra Mastropasqua; Raffaella Aloia; Chiara De Nicola; Peter A Mattei; Guido Di Marzio; Marta Di Nicola; Luca Di Antonio Journal: Int J Ophthalmol Date: 2017-10-18 Impact factor: 1.779
Authors: José Ignacio Fernández-Vigo; Bachar Kudsieh; Ana Macarro-Merino; Pedro Arriola-Villalobos; José María Martínez-de-la-Casa; Julián García-Feijóo; José Ángel Fernández-Vigo Journal: Eur J Ophthalmol Date: 2019-03-12 Impact factor: 2.597
Authors: Bingyao Tan; Jacqueline Chua; Emily Lin; Joyce Cheng; Alfred Gan; Xinwen Yao; Damon W K Wong; Charumathi Sabanayagam; Doric Wong; Choi Mun Chan; Tien Yin Wong; Leopold Schmetterer; Gavin S Tan Journal: JAMA Netw Open Date: 2020-01-03