Literature DB >> 36120416

Mitigating Membership Inference in Deep Learning Applications with High Dimensional Genomic Data.

Chonghao Zhang1, Luca Bonomi2.   

Abstract

The use of deep learning techniques in medical applications holds great promises for advancing health care. However, there are growing privacy concerns regarding what information about individual data contributors (i.e., patients in the training set) these deep models may reveal when shared with external users. In this work, we first investigate the membership privacy risks in sharing deep learning models for cancer genomics tasks, and then study the applicability of privacy-protecting strategies for mitigating these privacy risks.

Entities:  

Keywords:  Deep Learning; Genomic Data; Privacy

Year:  2022        PMID: 36120416      PMCID: PMC9473339          DOI: 10.1109/ichi54592.2022.00101

Source DB:  PubMed          Journal:  IEEE Int Conf Healthc Inform        ISSN: 2575-2626


  6 in total

Review 1.  Privacy challenges and research opportunities for genomic data sharing.

Authors:  Luca Bonomi; Yingxiang Huang; Lucila Ohno-Machado
Journal:  Nat Genet       Date:  2020-06-29       Impact factor: 38.330

2.  Genomic privacy and limits of individual detection in a pool.

Authors:  Sriram Sankararaman; Guillaume Obozinski; Michael I Jordan; Eran Halperin
Journal:  Nat Genet       Date:  2009-08-23       Impact factor: 38.330

3.  Deep-learning approach to identifying cancer subtypes using high-dimensional genomic data.

Authors:  Runpu Chen; Le Yang; Steve Goodison; Yijun Sun
Journal:  Bioinformatics       Date:  2020-03-01       Impact factor: 6.937

Review 4.  Routes for breaching and protecting genetic privacy.

Authors:  Yaniv Erlich; Arvind Narayanan
Journal:  Nat Rev Genet       Date:  2014-05-08       Impact factor: 53.242

5.  The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

Authors:  Christina Curtis; Sohrab P Shah; Suet-Feung Chin; Gulisa Turashvili; Oscar M Rueda; Mark J Dunning; Doug Speed; Andy G Lynch; Shamith Samarajiwa; Yinyin Yuan; Stefan Gräf; Gavin Ha; Gholamreza Haffari; Ali Bashashati; Roslin Russell; Steven McKinney; Anita Langerød; Andrew Green; Elena Provenzano; Gordon Wishart; Sarah Pinder; Peter Watson; Florian Markowetz; Leigh Murphy; Ian Ellis; Arnie Purushotham; Anne-Lise Børresen-Dale; James D Brenton; Simon Tavaré; Carlos Caldas; Samuel Aparicio
Journal:  Nature       Date:  2012-04-18       Impact factor: 49.962

6.  Resolving individuals contributing trace amounts of DNA to highly complex mixtures using high-density SNP genotyping microarrays.

Authors:  Nils Homer; Szabolcs Szelinger; Margot Redman; David Duggan; Waibhav Tembe; Jill Muehling; John V Pearson; Dietrich A Stephan; Stanley F Nelson; David W Craig
Journal:  PLoS Genet       Date:  2008-08-29       Impact factor: 5.917

  6 in total

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