Gerd Göstemeyer1, Mareike Preus2, Karim Elhennawy3, Falk Schwendicke4, Sebastian Paris2, Haitham Askar2. 1. Department of Operative, Preventive and Pediatric Dentistry, Charité - Universitätsmedizin Berlin, Assmannshauser Straße 4-6, 14197, Berlin, Germany. gerd.goestemeyer@charite.de. 2. Department of Operative, Preventive and Pediatric Dentistry, Charité - Universitätsmedizin Berlin, Assmannshauser Straße 4-6, 14197, Berlin, Germany. 3. Department of Orthodontics, Dentofacial Orthopedics and Pedodontics, Charité - Universitätsmedizin Berlin, Assmannshauser Straße 4-6, 14197, Berlin, Germany. 4. Department of Oral Diagnostics, Digital Health and Health Services Research, Charité - Universitätsmedizin Berlin, Assmannshauser Straße 4-6, 14197, Berlin, Germany.
Abstract
OBJECTIVES: The objective was to evaluate the diagnostic accuracy of radiographic evaluation (XR), visual-tactile assessment (VT), laser-fluorescence (LF) (DIAGNOdent Pen/KaVo), and near-infrared-light transillumination (NILT) (DIAGNOcam/KaVo) on proximal root caries lesions in vitro. METHODS: Two-hundred extracted permanent premolars and molars with and without proximal root caries lesions were allocated to 50 diagnostic models simulating the proximal contacts between teeth and mounted in a phantom dummy head. Two independent examiners used the diagnostic approaches to detect any or advanced root caries lesions, with histologic evaluation of the lesions serving as reference. Receiver operating characteristic (ROC) curves were employed, and sensitivity, specificity, and the area under the ROC curve (AUC) are calculated. Significant differences in mean AUCs between approaches were assumed if p < 0.05 (two-sample t-test). RESULTS: NILT was not applicable for proximal root caries detection. The sensitivity/specificity to detect any lesions was 0.81/0.63 for XR, 0.76/0.88 for VT and 0.81/0.95 for LF, and the sensitivity/specificity to detect advanced lesions was 0.43/0.94 for XR, 0.66/0.99 for VT, and 0.83/0.78 for LF, respectively. For both, any and advanced root caries lesions, mean AUCs for LF and VT were significantly higher compared to XR (p < 0.05). For any root caries lesions, LF was significantly more accurate than VT (p = 0.01), but not for advanced root caries lesions (p = 0.59). CONCLUSIONS: Under the in vitro conditions chosen, LF and VT were more accurate than XR to detect proximal root caries lesions, with LF being particularly useful for initial lesion stages. CLINICAL RELEVANCE: LF might be a useful diagnostic aid for proximal root caries diagnosis. Clinical studies are necessary to corroborate the findings.
OBJECTIVES: The objective was to evaluate the diagnostic accuracy of radiographic evaluation (XR), visual-tactile assessment (VT), laser-fluorescence (LF) (DIAGNOdent Pen/KaVo), and near-infrared-light transillumination (NILT) (DIAGNOcam/KaVo) on proximal root caries lesions in vitro. METHODS: Two-hundred extracted permanent premolars and molars with and without proximal root caries lesions were allocated to 50 diagnostic models simulating the proximal contacts between teeth and mounted in a phantom dummy head. Two independent examiners used the diagnostic approaches to detect any or advanced root caries lesions, with histologic evaluation of the lesions serving as reference. Receiver operating characteristic (ROC) curves were employed, and sensitivity, specificity, and the area under the ROC curve (AUC) are calculated. Significant differences in mean AUCs between approaches were assumed if p < 0.05 (two-sample t-test). RESULTS: NILT was not applicable for proximal root caries detection. The sensitivity/specificity to detect any lesions was 0.81/0.63 for XR, 0.76/0.88 for VT and 0.81/0.95 for LF, and the sensitivity/specificity to detect advanced lesions was 0.43/0.94 for XR, 0.66/0.99 for VT, and 0.83/0.78 for LF, respectively. For both, any and advanced root caries lesions, mean AUCs for LF and VT were significantly higher compared to XR (p < 0.05). For any root caries lesions, LF was significantly more accurate than VT (p = 0.01), but not for advanced root caries lesions (p = 0.59). CONCLUSIONS: Under the in vitro conditions chosen, LF and VT were more accurate than XR to detect proximal root caries lesions, with LF being particularly useful for initial lesion stages. CLINICAL RELEVANCE: LF might be a useful diagnostic aid for proximal root caries diagnosis. Clinical studies are necessary to corroborate the findings.
Authors: Pieternella C Bots-VantSpijker; Jacques N O Vanobbergen; Jos M G A Schols; Rob M H Schaub; Casper P Bots; Cees de Baat Journal: Community Dent Oral Epidemiol Date: 2013-09-18 Impact factor: 3.383
Authors: Mila Janjic Rankovic; Svetlana Kapor; Yegane Khazaei; Alexander Crispin; Ina Schüler; Felix Krause; Kim Ekstrand; Stavroula Michou; Florin Eggmann; Adrian Lussi; Marie-Charlotte Huysmans; Klaus Neuhaus; Jan Kühnisch Journal: Clin Oral Investig Date: 2021-09-04 Impact factor: 3.573
Authors: Svetlana Kapor; Mila Janjic Rankovic; Yegane Khazaei; Alexander Crispin; Ina Schüler; Felix Krause; Adrian Lussi; Klaus Neuhaus; Florin Eggmann; Stavroula Michou; Kim Ekstrand; Marie-Charlotte Huysmans; Jan Kühnisch Journal: Clin Oral Investig Date: 2021-06-14 Impact factor: 3.573