Literature DB >> 3610839

A new antibiotic, tautomycin.

X C Cheng, T Kihara, H Kusakabe, J Magae, Y Kobayashi, R P Fang, Z F Ni, Y C Shen, K Ko, I Yamaguchi.   

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Year:  1987        PMID： 3610839     DOI： 10.7164/antibiotics.40.907

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


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  15 in total

1.  Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

Authors:  Yinggang Luo; Wenli Li; Jianhua Ju; Qiuping Yuan; Noel R Peters; F Michael Hoffmann; Sheng-Xiong Huang; Tim S Bugni; Scott Rajski; Hiroyuki Osada; Ben Shen
Journal:  J Am Chem Soc       Date:  2010-05-19       Impact factor: 15.419

2.  SHP2 is a target of the immunosuppressant tautomycetin.

Authors:  Sijiu Liu; Zhihong Yu; Xiao Yu; Sheng-Xiong Huang; Yinggang Luo; Li Wu; Weihua Shen; Zhenyun Yang; Lina Wang; Andrea M Gunawan; Rebecca J Chan; Ben Shen; Zhong-Yin Zhang
Journal:  Chem Biol       Date:  2011-01-28

Review 3.  Biosynthesis, regulation, and engineering of a linear polyketide tautomycetin: a novel immunosuppressant in Streptomyces sp. CK4412.

Authors:  Si-Sun Choi; Hee-Ju Nah; Hye-Rim Pyeon; Eung-Soo Kim
Journal:  J Ind Microbiol Biotechnol       Date:  2016-10-12       Impact factor: 3.346

4.  Effects of modification of the hydrophobic C-1-C-16 segment of tautomycin on its affinity to type-1 and type-2A protein phosphatases.

Authors:  A Takai; K Tsuboi; M Koyasu; M Isobe
Journal:  Biochem J       Date:  2000-08-15       Impact factor: 3.857

5.  Inhibition of specific binding of okadaic acid to protein phosphatase 2A by microcystin-LR, calyculin-A and tautomycin: method of analysis of interactions of tight-binding ligands with target protein.

Authors:  A Takai; K Sasaki; H Nagai; G Mieskes; M Isobe; K Isono; T Yasumoto
Journal:  Biochem J       Date:  1995-03-15       Impact factor: 3.857

6.  Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.

Authors:  Matthew S Kelker; Rebecca Page; Wolfgang Peti
Journal:  J Mol Biol       Date:  2008-11-01       Impact factor: 5.469

7.  Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

Authors:  Jianhua Ju; Wenli Li; Qiuping Yuan; Noel R Peters; F Michael Hoffmann; Scott R Rajski; Hiroyuki Osada; Ben Shen
Journal:  Org Lett       Date:  2009-04-02       Impact factor: 6.005

8.  Tautomycin: an inhibitor of protein phosphatases 1 and 2A but not a tumor promoter on mouse skin and in rat glandular stomach.

Authors:  M Suganuma; S Okabe; E Sueoka; R Nishiwaki; A Komori; N Uda; K Isono; H Fujiki
Journal:  J Cancer Res Clin Oncol       Date:  1995       Impact factor: 4.553

9.  Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.

Authors:  Wenli Li; Jianhua Ju; Scott R Rajski; Hiroyuki Osada; Ben Shen
Journal:  J Biol Chem       Date:  2008-08-15       Impact factor: 5.157

10.  Tautomycetin and tautomycin suppress the growth of medullary thyroid cancer cells via inhibition of glycogen synthase kinase-3beta.

Authors:  Joel T Adler; Mackenzie Cook; Yinggang Luo; Susan C Pitt; Jianhua Ju; Wenli Li; Ben Shen; Muthusamy Kunnimalaiyaan; Herbert Chen
Journal:  Mol Cancer Ther       Date:  2009-04       Impact factor: 6.261
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