Literature DB >> 36068466

Pharmacogenomics Informs Cardiovascular Pharmacotherapy.

Mariana Babayeva1, Brigitte Azzi1, Zvi G Loewy2,3.   

Abstract

Precision medicine exemplifies the emergence of personalized treatment options which may benefit specific patient populations based upon their genetic makeup. Application of pharmacogenomics requires an understanding of how genetic variations impact pharmacokinetic and pharmacodynamic properties. This particular approach in pharmacotherapy is helpful because it can assist in and improve clinical decisions. Application of pharmacogenomics to cardiovascular pharmacotherapy provides for the ability of the medical provider to gain critical knowledge on a patient's response to various treatment options and risk of side effects.
© 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Genotype; Personalized medicine; Polymorphism

Mesh：

Year:  2022        PMID： 36068466     DOI： 10.1007/978-1-0716-2573-6_9

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  282 in total

1.  Associations between ADRB1 and CYP2D6 gene polymorphisms and the response to β-blocker therapy in hypertension.

Authors:  Dingchang Wu; Ganyang Li; Maoqing Deng; Wei Song; Xiaohua Huang; Xiaoru Guo; Zhengzheng Wu; Shiyang Wu; Jiasen Xu
Journal:  J Int Med Res       Date:  2015-03-30       Impact factor: 1.671

2.  A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients.

Authors:  Patrik Svensson-Färbom; Björn Wahlstrand; Peter Almgren; Jonas Dahlberg; Cristiano Fava; Sverre Kjeldsen; Thomas Hedner; Olle Melander
Journal:  J Hypertens       Date:  2011-02       Impact factor: 4.844

3.  Prevention of atrial fibrillation by bucindolol is dependent on the beta₁389 Arg/Gly adrenergic receptor polymorphism.

Authors:  Ryan G Aleong; William H Sauer; Gordon Davis; Guinevere A Murphy; J David Port; Inder S Anand; Mona Fiuzat; Christopher M O'Connor; William T Abraham; Stephen B Liggett; Michael R Bristow
Journal:  JACC Heart Fail       Date:  2013-08       Impact factor: 12.035

4.  A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure.

Authors:  Stephen B Liggett; Jeanne Mialet-Perez; Surai Thaneemit-Chen; Stewart A Weber; Scott M Greene; Danielle Hodne; Bradley Nelson; Jennifer Morrison; Michael J Domanski; Lynne E Wagoner; William T Abraham; Jeffrey L Anderson; John F Carlquist; Heidi J Krause-Steinrauf; Laura C Lazzeroni; J David Port; Philip W Lavori; Michael R Bristow
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-14       Impact factor: 11.205

Review 5.  NEDD4-2 and salt-sensitive hypertension.

Authors:  Federica Rizzo; Olivier Staub
Journal:  Curr Opin Nephrol Hypertens       Date:  2015-03       Impact factor: 2.894

6.  Genetic variation in NEDD4L, an epithelial sodium channel regulator, is associated with cardiovascular disease and cardiovascular death.

Authors:  Jonas Dahlberg; Marketa Sjögren; Bo Hedblad; Gunnar Engström; Olle Melander
Journal:  J Hypertens       Date:  2014-02       Impact factor: 4.844

7.  Association of variants in NEDD4L with blood pressure response and adverse cardiovascular outcomes in hypertensive patients treated with thiazide diuretics.

Authors:  Caitrin W McDonough; Sarah E Burbage; Julio D Duarte; Yan Gong; Taimour Y Langaee; Stephen T Turner; John G Gums; Arlene B Chapman; Kent R Bailey; Amber L Beitelshees; Eric Boerwinkle; Carl J Pepine; Rhonda M Cooper-DeHoff; Julie A Johnson
Journal:  J Hypertens       Date:  2013-04       Impact factor: 4.844

8.  Association of hypertension drug target genes with blood pressure and hypertension in 86,588 individuals.

Authors:  Andrew D Johnson; Christopher Newton-Cheh; Daniel I Chasman; Georg B Ehret; Toby Johnson; Lynda Rose; Kenneth Rice; Germaine C Verwoert; Lenore J Launer; Vilmundur Gudnason; Martin G Larson; Aravinda Chakravarti; Bruce M Psaty; Mark Caulfield; Cornelia M van Duijn; Paul M Ridker; Patricia B Munroe; Daniel Levy
Journal:  Hypertension       Date:  2011-03-28       Impact factor: 10.190

9.  Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Authors:  Santhi K Ganesh; Vinicius Tragante; Wei Guo; Yiran Guo; Matthew B Lanktree; Erin N Smith; Toby Johnson; Berta Almoguera Castillo; John Barnard; Jens Baumert; Yen-Pei Christy Chang; Clara C Elbers; Martin Farrall; Mary E Fischer; Nora Franceschini; Tom R Gaunt; Johannes M I H Gho; Christian Gieger; Yan Gong; Aaron Isaacs; Marcus E Kleber; Irene Mateo Leach; Caitrin W McDonough; Matthijs F L Meijs; Olle Mellander; Cliona M Molony; Ilja M Nolte; Sandosh Padmanabhan; Tom S Price; Ramakrishnan Rajagopalan; Jonathan Shaffer; Sonia Shah; Haiqing Shen; Nicole Soranzo; Peter J van der Most; Erik P A Van Iperen; Jessica Van Setten; Jessic A Van Setten; Judith M Vonk; Li Zhang; Amber L Beitelshees; Gerald S Berenson; Deepak L Bhatt; Jolanda M A Boer; Eric Boerwinkle; Ben Burkley; Amber Burt; Aravinda Chakravarti; Wei Chen; Rhonda M Cooper-Dehoff; Sean P Curtis; Albert Dreisbach; David Duggan; Georg B Ehret; Richard R Fabsitz; Myriam Fornage; Ervin Fox; Clement E Furlong; Ron T Gansevoort; Marten H Hofker; G Kees Hovingh; Susan A Kirkland; Kandice Kottke-Marchant; Abdullah Kutlar; Andrea Z Lacroix; Taimour Y Langaee; Yun R Li; Honghuang Lin; Kiang Liu; Steffi Maiwald; Rainer Malik; Gurunathan Murugesan; Christopher Newton-Cheh; Jeffery R O'Connell; N Charlotte Onland-Moret; Willem H Ouwehand; Walter Palmas; Brenda W Penninx; Carl J Pepine; Mary Pettinger; Joseph F Polak; Vasan S Ramachandran; Jane Ranchalis; Susan Redline; Paul M Ridker; Lynda M Rose; Hubert Scharnag; Nicholas J Schork; Daichi Shimbo; Alan R Shuldiner; Sathanur R Srinivasan; Ronald P Stolk; Herman A Taylor; Barbara Thorand; Mieke D Trip; Cornelia M van Duijn; W Monique Verschuren; Cisca Wijmenga; Bernhard R Winkelmann; Sharon Wyatt; J Hunter Young; Bernhard O Boehm; Mark J Caulfield; Daniel I Chasman; Karina W Davidson; Pieter A Doevendans; Garret A Fitzgerald; John G Gums; Hakon Hakonarson; Hans L Hillege; Thomas Illig; Gail P Jarvik; Julie A Johnson; John J P Kastelein; Wolfgang Koenig; Winfried März; Braxton D Mitchell; Sarah S Murray; Albertine J Oldehinkel; Daniel J Rader; Muredach P Reilly; Alex P Reiner; Eric E Schadt; Roy L Silverstein; Harold Snieder; Alice V Stanton; André G Uitterlinden; Pim van der Harst; Yvonne T van der Schouw; Nilesh J Samani; Andrew D Johnson; Patricia B Munroe; Paul I W de Bakker; Xiaofeng Zhu; Daniel Levy; Brendan J Keating; Folkert W Asselbergs
Journal:  Hum Mol Genet       Date:  2013-01-08       Impact factor: 6.150

10.  Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).

Authors:  Sonal Singh; Helen R Warren; Timo P Hiltunen; Caitrin W McDonough; Nihal El Rouby; Erika Salvi; Zhiying Wang; Tatiana Garofalidou; Frej Fyhrquist; Kimmo K Kontula; Valeria Glorioso; Roberta Zaninello; Nicola Glorioso; Carl J Pepine; Patricia B Munroe; Stephan T Turner; Arlene B Chapman; Eric Boerwinkle; Julie A Johnson; Yan Gong; Rhonda M Cooper-DeHoff
Journal:  J Am Heart Assoc       Date:  2019-08-19       Impact factor: 5.501
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