Literature DB >> 3606577

Direct assessment of brown adipose tissue as a site of systemic tri-iodothyronine production in the rat.

J A Fernandez, T Mampel, F Villarroya, R Iglesias.   

Abstract

Tri-iodothyronine (T3)production by interscapular brown fat was studied by measurements of arterio-venous differences and blood flow across the tissue in rats exposed to the following situations: controls, acute cold, chronic cold and starvation. Results demonstrate that brown adipose tissue is a source of systemic T3 in the rat and that the T3 release is modulated according to the physiological situation of the animal: increased in cold exposure and inhibited in starvation.

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Year:  1987        PMID: 3606577      PMCID: PMC1147845          DOI: 10.1042/bj2430281

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  26 in total

1.  Lowry determination of protein in the presence of Triton X-100.

Authors:  C Wang; R L Smith
Journal:  Anal Biochem       Date:  1975-02       Impact factor: 3.365

2.  A mitochondrial defect in brown adipose tissue of the obese (ob/ob) mouse: reduced binding of purine nucleotides and a failure to respond to cold by an increase in binding.

Authors:  J Himms-Hagen; M Desautels
Journal:  Biochem Biophys Res Commun       Date:  1978-07-28       Impact factor: 3.575

3.  Kinetic evidence suggesting two mechanisms for iodothyronine 5'-deiodination in rat cerebral cortex.

Authors:  T J Visser; J L Leonard; M M Kaplan; P R Larsen
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

4.  Qualitative and quantitative differences in the pathways of extrathyroidal triiodothyronine generation between euthyroid and hypothyroid rats.

Authors:  J E Silva; M B Gordon; F R Crantz; J L Leonard; P R Larsen
Journal:  J Clin Invest       Date:  1984-04       Impact factor: 14.808

5.  Thyroid hormone metabolism and the source of plasma triiodothyronine in 2-week-old rats: effects of thyroid status.

Authors:  J E Silva; P Matthews
Journal:  Endocrinology       Date:  1984-06       Impact factor: 4.736

6.  Adrenergic activation of triiodothyronine production in brown adipose tissue.

Authors:  J E Silva; P R Larsen
Journal:  Nature       Date:  1983 Oct 20-26       Impact factor: 49.962

7.  Brown fat activity in fasted and refed rats.

Authors:  N J Rothwell; M E Saville; M J Stock
Journal:  Biosci Rep       Date:  1984-04       Impact factor: 3.840

8.  Effect of acute exposure to cold on the activity of the hypothalamic-pituitary-thyroid system.

Authors:  E Hefco; L Krulich; P Illner; P R Larsen
Journal:  Endocrinology       Date:  1975-11       Impact factor: 4.736

9.  Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.

Authors:  T J Visser; M M Kaplan; J L Leonard; P R Larsen
Journal:  J Clin Invest       Date:  1983-04       Impact factor: 14.808

10.  Impaired basal and noradrenaline-induced iodothyronine 5'-deiodinase activity in brown adipose tissue from pregnant and lactating rats.

Authors:  M Giralt; F Villarroya; T Mampel; R Iglesias
Journal:  Biochem Biophys Res Commun       Date:  1986-08-14       Impact factor: 3.575

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  10 in total

1.  Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

Authors:  Elayne Hondares; Roser Iglesias; Albert Giralt; Frank J Gonzalez; Marta Giralt; Teresa Mampel; Francesc Villarroya
Journal:  J Biol Chem       Date:  2011-02-13       Impact factor: 5.157

Review 2.  Mechanisms linking adipose tissue inflammation to cardiac hypertrophy and fibrosis.

Authors:  Sarah R Anthony; Adrienne R Guarnieri; Anamarie Gozdiff; Robert N Helsley; Albert Phillip Owens; Michael Tranter
Journal:  Clin Sci (Lond)       Date:  2019-11-29       Impact factor: 6.124

Review 3.  Brown adipose tissue: The heat is on the heart.

Authors:  Robrecht Thoonen; Allyson G Hindle; Marielle Scherrer-Crosbie
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-04-15       Impact factor: 4.733

4.  Iodothyronine 5'-deiodinase activity as an early event of prenatal brown-fat differentiation in bovine development.

Authors:  M Giralt; L Casteilla; O Viñas; T Mampel; R Iglesias; J Robelin; F Villarroya
Journal:  Biochem J       Date:  1989-04-15       Impact factor: 3.857

5.  Iodothyronine 5'-deiodinase activity and thyroid hormone content in brown adipose tissue during the breeding cycle of the rat.

Authors:  O Viñas; M Giralt; M J Obregón; R Iglesias; F Villarroya; T Mampel
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

6.  Replacement therapy for hypothyroidism with thyroxine alone does not ensure euthyroidism in all tissues, as studied in thyroidectomized rats.

Authors:  H F Escobar-Morreale; M J Obregón; F Escobar del Rey; G Morreale de Escobar
Journal:  J Clin Invest       Date:  1995-12       Impact factor: 14.808

7.  Factors influencing the altered thermogenic response of rat brown adipose tissue in streptozotocin-diabetes.

Authors:  Z Jamal; E D Saggerson
Journal:  Biochem J       Date:  1988-01-15       Impact factor: 3.857

8.  Amino acid and glucose uptake by rat brown adipose tissue. Effect of cold-exposure and acclimation.

Authors:  F J López-Soriano; J A Fernández-López; T Mampel; F Villarroya; R Iglesias; M Alemany
Journal:  Biochem J       Date:  1988-06-15       Impact factor: 3.857

Review 9.  MicroRNA Regulation of Brown Adipogenesis and Thermogenic Energy Expenditure.

Authors:  Farnaz Shamsi; Hongbin Zhang; Yu-Hua Tseng
Journal:  Front Endocrinol (Lausanne)       Date:  2017-08-23       Impact factor: 5.555

Review 10.  Thermogenesis in Adipose Tissue Activated by Thyroid Hormone.

Authors:  Winifred W Yau; Paul M Yen
Journal:  Int J Mol Sci       Date:  2020-04-24       Impact factor: 5.923

  10 in total

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