Literature DB >> 27084389

Brown adipose tissue: The heat is on the heart.

Robrecht Thoonen1, Allyson G Hindle2, Marielle Scherrer-Crosbie3.   

Abstract

The study of brown adipose tissue (BAT) has gained significant scientific interest since the discovery of functional BAT in adult humans. The thermogenic properties of BAT are well recognized; however, data generated in the last decade in both rodents and humans reveal therapeutic potential for BAT against metabolic disorders and obesity. Here we review the current literature in light of a potential role for BAT in beneficially mediating cardiovascular health. We focus mainly on BAT's actions in obesity, vascular tone, and glucose and lipid metabolism. Furthermore, we discuss the recently discovered endocrine factors that have a potential beneficial role in cardiovascular health. These BAT-secreted factors may have a favorable effect against cardiovascular risk either through their metabolic role or by directly affecting the heart.
Copyright © 2016 the American Physiological Society.

Entities:  

Keywords:  cardiovascular; diabetes; endocrine function; obesity

Mesh：

Year:  2016        PMID： 27084389      PMCID： PMC6345214          DOI： 10.1152/ajpheart.00698.2015

Source DB:  PubMed          Journal:  Am J Physiol Heart Circ Physiol        ISSN： 0363-6135            Impact factor:   4.733


  201 in total

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Authors:  J Nedergaard; V Golozoubova; A Matthias; A Asadi; A Jacobsson; B Cannon
Journal:  Biochim Biophys Acta       Date:  2001-03-01

2.  Perivascular inflammation after balloon angioplasty of porcine coronary arteries.

Authors:  E Okamoto; T Couse; H De Leon; J Vinten-Johansen; R B Goodman; N A Scott; J N Wilcox
Journal:  Circulation       Date:  2001-10-30       Impact factor: 29.690

3.  The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue.

Authors:  L A de Jesus; S D Carvalho; M O Ribeiro; M Schneider; S W Kim; J W Harney; P R Larsen; A C Bianco
Journal:  J Clin Invest       Date:  2001-11       Impact factor: 14.808

4.  TH-, NPY-, SP-, and CGRP-immunoreactive nerves in interscapular brown adipose tissue of adult rats acclimated at different temperatures: an immunohistochemical study.

Authors:  R De Matteis; D Ricquier; S Cinti
Journal:  J Neurocytol       Date:  1998-12

5.  Physiological effects of heat and cold.

Authors:  S ROBINSON
Journal:  Annu Rev Physiol       Date:  1952       Impact factor: 19.318

6.  Thermogenic responses in brown fat cells are fully UCP1-dependent. UCP2 or UCP3 do not substitute for UCP1 in adrenergically or fatty scid-induced thermogenesis.

Authors:  A Matthias; K B Ohlson; J M Fredriksson; A Jacobsson; J Nedergaard; B Cannon
Journal:  J Biol Chem       Date:  2000-08-18       Impact factor: 5.157

7.  Identification of a novel FGF, FGF-21, preferentially expressed in the liver.

Authors:  T Nishimura; Y Nakatake; M Konishi; N Itoh
Journal:  Biochim Biophys Acta       Date:  2000-06-21

8.  Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold.

Authors:  V Golozoubova; E Hohtola; A Matthias; A Jacobsson; B Cannon; J Nedergaard
Journal:  FASEB J       Date:  2001-07-09       Impact factor: 5.191

9.  betaAR signaling required for diet-induced thermogenesis and obesity resistance.

Authors:  Eric S Bachman; Harveen Dhillon; Chen-Yu Zhang; Saverio Cinti; Antonio C Bianco; Brian K Kobilka; Bradford B Lowell
Journal:  Science       Date:  2002-08-02       Impact factor: 47.728

10.  Paradoxical resistance to diet-induced obesity in UCP1-deficient mice.

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Journal:  J Clin Invest       Date:  2003-02       Impact factor: 14.808
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  16 in total

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Journal:  Clin Sci (Lond)       Date:  2019-11-29       Impact factor: 6.124

Review 3.  Epicardial adipose tissue as a mediator of cardiac arrhythmias.

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Journal:  Am J Physiol Heart Circ Physiol       Date:  2021-12-10       Impact factor: 4.733

Review 4.  Influences of ovarian hormones on physiological responses to cold in women.

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Journal:  Temperature (Austin)       Date:  2021-09-14

5.  Calcium cycling as a mediator of thermogenic metabolism in adipose tissue.

Authors:  Adrienne R Guarnieri; Tyler W Benson; Michael Tranter
Journal:  Mol Pharmacol       Date:  2022-05-03       Impact factor: 4.054

6.  PET imaging study of brown adipose tissue (BAT) activity in mice devoid of receptor for advanced glycation end products (RAGE).

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Journal:  J Biosci       Date:  2019-09       Impact factor: 1.826

7.  Drinking Molecular Hydrogen Water Is Beneficial to Cardiovascular Function in Diet-Induced Obesity Mice.

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8.  Role of Perivascular Adipose Tissue and Exercise on Arterial Function with Obesity.

Authors:  Samuel Y Boateng; I Mark Olfert; Paul D Chantler
Journal:  Exerc Sport Sci Rev       Date:  2021-07-01       Impact factor: 6.642

9.  Elevated Omentin Serum Levels Predict Long-Term Survival in Critically Ill Patients.

Authors:  Mark Luedde; Fabian Benz; Jennifer Niedeggen; Mihael Vucur; Hans-Joerg Hippe; Martina E Spehlmann; Florian Schueller; Sven Loosen; Norbert Frey; Christian Trautwein; Alexander Koch; Tom Luedde; Frank Tacke; Christoph Roderburg
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Review 10.  Role of natriuretic peptides in the cardiovascular-adipose communication: a tale of two organs.

Authors:  Natalia Lucía Rukavina Mikusic; Nicolás Martín Kouyoumdzian; Ana María Puyó; Belisario Enrique Fernández; Marcelo Roberto Choi
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