Literature DB >> 36060485

Complications associated with iliosacral lymphadenectomy in dogs with metastatic apocrine gland anal sac adenocarcinoma.

Yael Huerta1, Carlos H De Mello Souza1, Laura E Selmic1, Alysha McGrath1, Owen T Skinner1, Katelin V Dark1, Marine Traverson1, William L Snell1, Elizabeth A Maxwell1, Judith Bertran1, Michelle M M Hasiuk1.   

Abstract

Objective: To report intraoperative and immediate postoperative complications associated with removal of metastatic iliosacral lymph nodes in dogs with apocrine gland anal sac adenocarcinoma. Animals: There were 136 client-owned dogs in the study. Procedure: Retrospective multi-institutional study. The database of collaborating institutions was searched for dogs with metastatic apocrine gland anal sac adenocarcinoma that underwent lymphadenectomy for removal of one or more iliosacral lymph nodes. Information of signalment, hematological abnormalities, abdominal computed tomography or ultrasound findings, number and size of enlarged lymph nodes, intraoperative and postoperative complications, treatment and outcome were collected.
Results: The overall complication rate associated with metastatic iliosacral lymphadenectomy was 26.1%. The only intraoperative complication recorded was hemorrhage and was reported in 24 (17.6%) surgeries, 11 (45.8%) of which received a blood transfusion. Postoperative complications were reported in 10.4% of surgeries, and included edema formation (n = 4, 2.6%), unilateral or bilateral paraparesis (n = 4, 2.6%), hypotension (n = 3, 2.0%), surgical site infection (n = 2, 1.3%), abdominal incision dehiscence (n = 1, 0.6%), urinary incontinence (n = 1, 0.6%), and death (n = 1, 0.6%). The size of the iliosacral lymph nodes was significantly associated with a greater risk of complications, hemorrhage, and the need of transfusion during lymphadenectomy for metastatic apocrine gland anal sac adenocarcinoma.
Conclusion: Complications associated with iliosacral lymphadenectomy for metastatic apocrine gland anal sac adenocarcinoma are relatively common and mostly relate to hemorrhage. These complications are significantly associated with the size of the extirpated metastatic lymph nodes. Clinical relevance: This retrospective study provides information for the clinician regarding the potential surgical complications for extirpation of metastatic iliosacral lymph nodes. These complications, although not common, can be severe and should be discussed with owners before surgery. Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.

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Year:  2022        PMID: 36060485      PMCID: PMC9377189     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.075


  20 in total

1.  Ultrasound and computed tomography of the iliosacral lymphatic centre in dogs with anal sac gland carcinoma.

Authors:  R E Pollard; M C Fuller; M A Steffey
Journal:  Vet Comp Oncol       Date:  2015-12-14       Impact factor: 2.613

2.  Definition and Classification of Intraoperative Complications (CLASSIC): Delphi Study and Pilot Evaluation.

Authors:  Rachel Rosenthal; Henry Hoffmann; Pierre-Alain Clavien; Heiner C Bucher; Salome Dell-Kuster
Journal:  World J Surg       Date:  2015-07       Impact factor: 3.352

3.  Canine anal sac adenocarcinomas: clinical presentation and response to therapy.

Authors:  Peter F Bennett; Denis B DeNicola; Patty Bonney; Nita W Glickman; Deborah W Knapp
Journal:  J Vet Intern Med       Date:  2002 Jan-Feb       Impact factor: 3.333

4.  Anal sac gland adenocarcinoma in the dog: 14 cases.

Authors:  M H Goldschmidt; C Zoltowski
Journal:  J Small Anim Pract       Date:  1981-03       Impact factor: 1.522

5.  Anal sac tumours of the dog and their response to cytoreductive surgery and chemotherapy.

Authors:  S G Emms
Journal:  Aust Vet J       Date:  2005-06       Impact factor: 1.281

6.  Treatment of advanced canine anal sac adenocarcinoma with hypofractionated radiation therapy: 77 cases (1999-2013).

Authors:  B McQuown; M A Keyerleber; K Rosen; M C McEntee; K E Burgess
Journal:  Vet Comp Oncol       Date:  2016-03-16       Impact factor: 2.613

7.  Postoperative radiotherapy and mitoxantrone for anal sac adenocarcinoma in the dog: 15 cases (1991-2001).

Authors:  M M Turek; L J Forrest; W M Adams; S C Helfand; D M Vail
Journal:  Vet Comp Oncol       Date:  2003-06       Impact factor: 2.613

8.  Utility of Computed Tomography versus Abdominal Ultrasound Examination to Identify Iliosacral Lymphadenomegaly in Dogs with Apocrine Gland Adenocarcinoma of the Anal Sac.

Authors:  S Palladino; M A Keyerleber; R G King; K E Burgess
Journal:  J Vet Intern Med       Date:  2016-10-24       Impact factor: 3.333

9.  A systematic review of criteria used to report complications in soft tissue and oncologic surgical clinical research studies in dogs and cats.

Authors:  Christelle M Follette; Michelle A Giuffrida; Ingrid M Balsa; William T N Culp; Philipp D Mayhew; Michelle L Oblak; Ameet Singh; Michele A Steffey
Journal:  Vet Surg       Date:  2019-07-09       Impact factor: 1.495

10.  Post-operative complications following apocrine gland anal sac adenocarcinoma resection in dogs.

Authors:  Allyson Sterman; J Ryan Butler; Aidan Chambers; Rachel Dickson; Josephine Dornbusch; Megan Mickelson; Laura Selmic; Valerie Scharf; Ariel Schlag; Owen Skinner; Arathi Vinayak; Brandan Wustefeld Janssens
Journal:  Vet Comp Oncol       Date:  2021-07-29       Impact factor: 2.613

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