Literature DB >> 36060359

Hypospadias: A Comprehensive Review Including Its Embryology, Etiology and Surgical Techniques.

Sattam A Halaseh1, Shahed Halaseh2, Mohannad Ashour3.   

Abstract

Hypospadias is among the most prevalent urogenital malformations in male newborns. It is characterized by the displacement of the urethral meatus to the ventral side of the penis, an aberrant ventral curve of the penis referred to as "chordee," and an abnormally arranged foreskin with a "hood" found dorsally and lacking foreskin ventrally. Patients may have an extra genitourinary abnormality based on the area of the lesion. In around 70% of cases, the urethral meatus is positioned distally to the shaft, representing a milder form of the disease. The remaining 30% of cases are located proximally, are more complicated, and require further evaluation. Although the origin of hypospadias is mostly obscure, several suggestions exist about genetic susceptibility and hormonal factors. The objective of hypospadias restoration is to restore aesthetic and functional regularity, and surgery is currently advised at a young age, mostly between six and 18 months. At any age, hypospadias can be repaired with an equivalent risk of complications, functional outcomes, and aesthetic outcomes. However, the best age of treatment is still undetermined. Even though the long-term effects on appearance and sexual function are usually good, males may be less likely to make the first move after rectification. Also, people who have hypospadias treated are twice as likely to have problems with their lower urinary tract. These problems can last for years after the initial repair.
Copyright © 2022, Halaseh et al.

Entities:  

Keywords:  external genital development; hypospadias; hypospadias repair; outcome; pediatric suregery; penis

Year:  2022        PMID: 36060359      PMCID: PMC9428502          DOI: 10.7759/cureus.27544

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  78 in total

1.  One-stage hypospadias repair. Experience with 544 cases.

Authors:  A M Ghali; E M el-Malik; T al-Malki; A H Ibrahim
Journal:  Eur Urol       Date:  1999-11       Impact factor: 20.096

2.  Urethral development in the fetal rabbit and induction of hypospadias: a model for human development.

Authors:  E A Kurzrock; P Jegatheesan; G R Cunha; L S Baskin
Journal:  J Urol       Date:  2000-11       Impact factor: 7.450

Review 3.  Current hypospadias management: Diagnosis, surgical management, and long-term patient-centred outcomes.

Authors:  Melise A Keays; Sumit Dave
Journal:  Can Urol Assoc J       Date:  2017 Jan-Feb       Impact factor: 1.862

4.  Impact of patient age on distal hypospadias repair: a surgical perspective.

Authors:  Adam E Perlmutter; Rocco Morabito; William F Tarry
Journal:  Urology       Date:  2006-09-18       Impact factor: 2.649

Review 5.  Snodgrass technique for hypospadias repair.

Authors:  Warren T Snodgrass
Journal:  BJU Int       Date:  2005-03       Impact factor: 5.588

6.  The slit-like adjusted Mathieu technique for distal hypospadias.

Authors:  Ahmed T Hadidi
Journal:  J Pediatr Surg       Date:  2012-03       Impact factor: 2.545

7.  MAGPI (meatoplasty and glanuloplasty): a procedure for subcoronal hypospadias.

Authors:  J W Duckett
Journal:  Urol Clin North Am       Date:  1981-10       Impact factor: 2.241

8.  Androgen receptor-mediated inhibition of cutaneous wound healing.

Authors:  Gillian S Ashcroft; Stuart J Mills
Journal:  J Clin Invest       Date:  2002-09       Impact factor: 14.808

Review 9.  The Genetic and Environmental Factors Underlying Hypospadias.

Authors:  Aurore Bouty; Katie L Ayers; Andrew Pask; Yves Heloury; Andrew H Sinclair
Journal:  Sex Dev       Date:  2015-11-28       Impact factor: 1.824

10.  Hypospadias hidden by a complete prepuce.

Authors:  D A Hatch; M Maizels; M R Zaontz; C F Firlit
Journal:  Surg Gynecol Obstet       Date:  1989-09
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