| Literature DB >> 36058969 |
O V Kazakov1, A V Kabakov2, A F Poveshchenko2, V V Kononchuk3, D N Strunkin3, L F Gulyaeva3, V I Konenkov2.
Abstract
The expression of microRNA (miR-21, miR-221, miR-27a, and miR-429) was studied normal and tumor breast tissues of female Wistar rats before and after photodynamic therapy. In breast cancer, the levels of oncogenic microRNA (miR-21, miR-221, and miR-27a) were increased, while the level of tumor-suppressing miR-429 was reduced in comparison with the intact group. After photodynamic therapy, suppression of the expression levels of oncogenic microRNAs (miR-21, miR-221, and miR-27a) was noted. The level of tumor-suppressing miR-429 in breast tumor tissues remained reduced, as in the untreated breast cancer group.Entities:
Keywords: breast cancer; microRNA; photodynamic therapy
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Year: 2022 PMID： 36058969 DOI： 10.1007/s10517-022-05584-2
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.737