Literature DB >> 3604260

The metabolism of 14C-labelled trimethylamine and its N-oxide in man.

M Al-Waiz, S C Mitchell, J R Idle, R L Smith.   

Abstract

The metabolism and elimination of 14C-labelled trimethylamine and its N-oxide (100 mg orally) were studied in three male volunteers. For both compounds the urine was the major route of elimination, with 95% of the administered 14C being voided in the first 24 h. No radioactivity was found in expired air. The majority (greater than 95%) of the urinary 14C from both compounds was excreted as trimethylamine N-oxide.

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Year:  1987        PMID： 3604260     DOI： 10.3109/00498258709043962

Source DB:  PubMed          Journal:  Xenobiotica        ISSN： 0049-8254            Impact factor:   1.908


  33 in total

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