Xiao-Jin Gao1,2, Xiao-Lin Peng1, Yu-Jiao Wang1, Wei-Min He3. 1. Department of Ophthalmology, West China School of Medicine, Sichuan University, Chengdu, Sichuan Province, China. 2. Department of Ophthalmology, Chengdu First People's Hospital, Chengdu, China. 3. Department of Ophthalmology, West China School of Medicine, Sichuan University, Chengdu, Sichuan Province, China. hewm888@hotmail.com.
Abstract
BACKGROUND: SFTs are thought to have an unpredictable clinical course and currently have no recognized prognostic criterion. Our study aimed to determine the relationship between clinicopathological characteristics and the prognosis of patients with orbital SFTs. METHODS: The clinicopathological features of these patients were extracted from clinical records. The relationships between these features and prognosis were analysed. RESULTS: The positive rates of CD34, CD99, Blc2, and STAT6 expression were 90.3%, 90.3%, 83.9%, and 100%, respectively. The tumour recurrence rate was 38.7%. A higher recurrence rate was observed in patients with Ki67 index ≥ 5 (56.25% vs. 20%, P = 0.038). CONCLUSION: A Ki67 index ≥ 5 was an effective parameter for predicting tumour recurrence of orbital SFTs. Close follow-up is needed for these patients.
BACKGROUND: SFTs are thought to have an unpredictable clinical course and currently have no recognized prognostic criterion. Our study aimed to determine the relationship between clinicopathological characteristics and the prognosis of patients with orbital SFTs. METHODS: The clinicopathological features of these patients were extracted from clinical records. The relationships between these features and prognosis were analysed. RESULTS: The positive rates of CD34, CD99, Blc2, and STAT6 expression were 90.3%, 90.3%, 83.9%, and 100%, respectively. The tumour recurrence rate was 38.7%. A higher recurrence rate was observed in patients with Ki67 index ≥ 5 (56.25% vs. 20%, P = 0.038). CONCLUSION: A Ki67 index ≥ 5 was an effective parameter for predicting tumour recurrence of orbital SFTs. Close follow-up is needed for these patients.
Authors: Román Carlos; Bruno Augusto Benevenuto de Andrade; Nathalie Henriques Silva Canedo; Aline Corrêa Abrahão; Michelle Agostini; Oslei Paes de Almeida; Mário José Romañach Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Date: 2015-11-14