| Literature DB >> 3600497 |
P Valenti, P Visca, G Antonini, N Orsi, E Antonini.
Abstract
The antibacterial activity of metal complexes of ovotransferrin was tested "in vitro" against different bacterial species and the Zn2+ saturated ovotransferrin appeared to be the most active by comparison with the apo-protein and other metal complexes. Appropriate controls showed that such an effect was neither due to Zn2+ ions, nor to iron deprivation, but to a specific activity of the Zn-ovotransferrin complex. This antibacterial activity required a direct contact of Zn-ovotransferrin with the bacterial surface. In vivo experiments confirmed the higher antibacterial activity of Zn-ovotransferrin as compared with the apo-form.Entities:
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Year: 1987 PMID: 3600497 DOI: 10.1007/bf00193893
Source DB: PubMed Journal: Med Microbiol Immunol ISSN: 0300-8584 Impact factor: 3.402