Literature DB >> 327545

A bactericidal effect for human lactoferrin.

R R Arnold, M F Cole, J R McGhee.   

Abstract

Streptococcus mutans and Vibrio cholerae, but not Escherichia coli, were killed by incubation with purified human apolactoferrin. Concentrations of lactoferrin below that necessary for total inhibition resulted in a marked reduction in viable colony-forming units. This bactericidal effect was contingent upon the metal-chelating properties of the lactoferrin molecule.

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Year:  1977        PMID: 327545     DOI: 10.1126/science.327545

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  126 in total

Review 1.  Antimicrobial polypeptides in host defense of the respiratory tract.

Authors:  Tomas Ganz
Journal:  J Clin Invest       Date:  2002-03       Impact factor: 14.808

2.  Both family 1 and family 2 PspA proteins can inhibit complement deposition and confer virulence to a capsular serotype 3 strain of Streptococcus pneumoniae.

Authors:  Bing Ren; Alexander J Szalai; Orlanda Thomas; Susan K Hollingshead; David E Briles
Journal:  Infect Immun       Date:  2003-01       Impact factor: 3.441

Review 3.  Lysosomal enzymes of phagocytes and the mechanism of their release.

Authors:  M Ferencík; J Stefanovic
Journal:  Folia Microbiol (Praha)       Date:  1979       Impact factor: 2.099

4.  Lactoferrin concentration in milk of bovine clinical mastitis.

Authors:  K Kawai; S Hagiwara; A Anri; H Nagahata
Journal:  Vet Res Commun       Date:  1999-11       Impact factor: 2.459

5.  Serine protease PrtA from Streptococcus pneumoniae plays a role in the killing of S. pneumoniae by apolactoferrin.

Authors:  Shaper Mirza; Landon Wilson; William H Benjamin; Jan Novak; Stephen Barnes; Susan K Hollingshead; David E Briles
Journal:  Infect Immun       Date:  2011-03-21       Impact factor: 3.441

6.  Killing of gram-negative bacteria by lactoferrin and lysozyme.

Authors:  R T Ellison; T J Giehl
Journal:  J Clin Invest       Date:  1991-10       Impact factor: 14.808

7.  Influence of lactoferrin on the entry process of Escherichia coli HB101 (pRI203) in HeLa cells.

Authors:  C Longhi; M P Conte; L Seganti; M Polidoro; A Alfsen; P Valenti
Journal:  Med Microbiol Immunol       Date:  1993-03       Impact factor: 3.402

8.  Lactotransferrin immunocytochemistry in Alzheimer and normal human brain.

Authors:  T Kawamata; I Tooyama; T Yamada; D G Walker; P L McGeer
Journal:  Am J Pathol       Date:  1993-05       Impact factor: 4.307

9.  Bactericidal activity of human lactoferrin: influence of physical conditions and metabolic state of the target microorganism.

Authors:  R R Arnold; J E Russell; W J Champion; J J Gauthier
Journal:  Infect Immun       Date:  1981-05       Impact factor: 3.441

10.  Glycans of bovine lactoferrin function as receptors for the type 1 fimbrial lectin of Escherichia coli.

Authors:  S Teraguchi; K Shin; Y Fukuwatari; S Shimamura
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441

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