Literature DB >> 36004016

Skeletal Mets From Squamous Cell Carcinoma of the Lower Limb: A Case Report.

Yasmeen Alanazi1, Asem Shadid1, Salman T Almalki2, Hatoon Bakhribah3.   

Abstract

Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer worldwide and one of the most capable of metastasis. The bone is a common metastatic site of cancers, which is a major cause of morbidity, with an estimated 350,000 people dying yearly from bone metastases. However, bone metastasis from an SCC in the lower limb is rarely reported in the literature and the role of systemic chemotherapy is not well established. We report a case of a 72-year-old gentleman with an SCC metastasis of the bone. This patient received six cycles of platinum-based chemotherapy with no surgical or radiation intervention.
Copyright © 2022, Alanazi et al.

Entities:  

Keywords:  bone metastasis; immunotherapy; lower limb; squamous cell carcinoma (scc); vitiligo

Year:  2022        PMID: 36004016      PMCID: PMC9392849          DOI: 10.7759/cureus.27155

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  13 in total

Review 1.  Bone metastasis: mechanisms and therapeutic opportunities.

Authors:  Larry J Suva; Charity Washam; Richard W Nicholas; Robert J Griffin
Journal:  Nat Rev Endocrinol       Date:  2011-01-04       Impact factor: 43.330

2.  Inverse Relationship between Vitiligo-Related Genes and Skin Cancer Risk.

Authors:  Wenting Wu; Christopher I Amos; Jeffrey E Lee; Qingyi Wei; Kavita Y Sarin; Jiali Han
Journal:  J Invest Dermatol       Date:  2018-03-23       Impact factor: 8.551

Review 3.  Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends.

Authors:  Joseph R Kallini; Nouran Hamed; Amor Khachemoune
Journal:  Int J Dermatol       Date:  2014-11-27       Impact factor: 2.736

4.  Cutaneous squamous cell carcinomas of the lower extremity: a distinct subset of squamous cell carcinomas.

Authors:  Changhyun Kim; Christine J Ko; David J Leffell
Journal:  J Am Acad Dermatol       Date:  2013-11-05       Impact factor: 11.527

5.  Incidence of nonmelanoma skin cancer in a cohort of patients with vitiligo.

Authors:  Camile L Hexsel; Melody J Eide; Christine C Johnson; Richard Krajenta; Gordon Jacobsen; Iltefat Hamzavi; Henry W Lim
Journal:  J Am Acad Dermatol       Date:  2009-04-17       Impact factor: 11.527

6.  Analysis of risk factors determining prognosis of cutaneous squamous-cell carcinoma: a prospective study.

Authors:  Kay D Brantsch; Christoph Meisner; Birgitt Schönfisch; Birgit Trilling; Jörg Wehner-Caroli; Martin Röcken; Helmut Breuninger
Journal:  Lancet Oncol       Date:  2008-07-09       Impact factor: 41.316

7.  Systemic Therapy in Advanced Cutaneous Squamous Cell Carcinoma (CSCC): The Roswell Park Experience and a Review of the Literature.

Authors:  Anthony Jarkowski; Ryan Hare; Peter Loud; Joseph J Skitzki; John M Kane; Kilian S May; Nathalie C Zeitouni; Jill Nestico; Karen L Vona; Adrienne Groman; Nikhil I Khushalani
Journal:  Am J Clin Oncol       Date:  2016-12       Impact factor: 2.339

8.  Cutaneous Squamous Cell Carcinomas of the Lower Extremities Show Distinct Clinical and Pathologic Features.

Authors:  Jason F Solus; George F Murphy; Stefan Kraft
Journal:  Int J Surg Pathol       Date:  2015-08-10       Impact factor: 1.271

9.  Squamous cell carcinoma of the legs in African Americans.

Authors:  Calvin O McCall; Suephy C Chen
Journal:  J Am Acad Dermatol       Date:  2002-10       Impact factor: 11.527

Review 10.  Cutaneous squamous cell carcinoma.

Authors:  Jorge Garcia-Zuazaga; Suzanne M Olbricht
Journal:  Adv Dermatol       Date:  2008
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