Literature DB >> 35991859

Impact of comprehensive care on health care use among a cohort of marginalized people living with hepatitis C in Toronto.

Erin Mandel1, Claire E Kendall2,3, Kate Mason4, Mary Guyton5, Bernadette Lettner4, Jennifer Broad4, Jason Altenberg4, Jessy Donelle6, Jeff Powis4,7.   

Abstract

Background: The majority of new hepatitis C (HCV) cases occur among people who inject drugs. In recent years, multidisciplinary models of HCV treatment have emerged that demonstrate successful treatment outcomes for this population, as well as broad positive individual- and system-level impacts. Our objective was to evaluate changes in health care use among a cohort of people living with HCV before and after engagement with one such program.
Methods: Program data were uniquely linked to provincial health administrative databases. Rates of emergency department (ED) visits and hospital admissions of clients from 2011 through 2015 (N = 103) were evaluated using linkages with administrative data for the 2 years before and after program initiation. Data were evaluated using negative binomial regression models with a covariance structure to account for within-individual correlations.
Results: Of participants, 72.8% were men (mean age 47 years), and 38% experienced high rates of physical and mental health comorbidity (Aggregated Diagnosis Group score ≥10). Female clients had significantly fewer ED visits 2 years after program initiation (5.04 versus 3.12; risk ratio [RR] 0.61 [95% CI 0.44% to 0.86%]). ED visits for infectious diseases and soft tissue injury were significantly lower for the cohort overall (RRs 0.58 0.51 [95% CIs 0.35% to 0.95% and 0.29% to 0.90%], respectively).
Conclusion: Co-locating HCV treatment within comprehensive primary care and harm reduction services appears to have benefits beyond HCV, including a reduction in ED visits among women and a decrease in ED visits for soft tissue infections for all participants.
Copyright © 2020 Canadian Association for the Study of the Liver.

Entities:  

Keywords:  community-based treatment models; emergency department use; health administrative data; health care models; hepatitis C; social determinants of health; substance use

Year:  2020        PMID: 35991859      PMCID: PMC9202786          DOI: 10.3138/canlivj.2019-0021

Source DB:  PubMed          Journal:  Can Liver J        ISSN: 2561-4444


  28 in total

Review 1.  Housing and health: time again for public health action.

Authors:  James Krieger; Donna L Higgins
Journal:  Am J Public Health       Date:  2002-05       Impact factor: 9.308

2.  Understanding real-world adherence in the directly acting antiviral era: A prospective evaluation of adherence among people with a history of drug use at a community-based program in Toronto, Canada.

Authors:  Kate Mason; Zoë Dodd; Mary Guyton; Paula Tookey; Bernadette Lettner; John Matelski; Sanjeev Sockalingam; Jason Altenberg; Jeff Powis
Journal:  Int J Drug Policy       Date:  2017-06-12

3.  Beyond viral response: A prospective evaluation of a community-based, multi-disciplinary, peer-driven model of HCV treatment and support.

Authors:  Kate Mason; Zoë Dodd; Sanjeev Sockalingam; Jason Altenberg; Christopher Meaney; Peggy Millson; Jeff Powis
Journal:  Int J Drug Policy       Date:  2015-04-29

Review 4.  Women Who Use or Inject Drugs: An Action Agenda for Women-Specific, Multilevel, and Combination HIV Prevention and Research.

Authors:  Nabila El-Bassel; Steffanie A Strathdee
Journal:  J Acquir Immune Defic Syndr       Date:  2015-06-01       Impact factor: 3.731

Review 5.  Understanding barriers to hepatitis C virus care and stigmatization from a social perspective.

Authors:  Carla Treloar; Jake Rance; Markus Backmund
Journal:  Clin Infect Dis       Date:  2013-08       Impact factor: 9.079

6.  Drug users seeking emergency care for soft tissue infection at high risk for subsequent hospitalization and death.

Authors:  Ingrid A Binswanger; Traci A Takahashi; Katharine Bradley; Timothy H Dellit; Kathryn L Benton; Joseph O Merrill
Journal:  J Stud Alcohol Drugs       Date:  2008-11       Impact factor: 2.582

7.  Continued low uptake of treatment for hepatitis C virus infection in a large community-based cohort of inner city residents.

Authors:  Maryam Alavi; Jesse D Raffa; Gregory D Deans; Calvin Lai; Mel Krajden; Gregory J Dore; Mark W Tyndall; Jason Grebely
Journal:  Liver Int       Date:  2013-11-20       Impact factor: 5.828

8.  Why sex and gender matter in implementation research.

Authors:  Cara Tannenbaum; Lorraine Greaves; Ian D Graham
Journal:  BMC Med Res Methodol       Date:  2016-10-27       Impact factor: 4.615

9.  Estimated prevalence of Hepatitis C Virus infection in Canada, 2011.

Authors:  M Trubnikov; P Yan; C Archibald
Journal:  Can Commun Dis Rep       Date:  2014-12-18

10.  A cross-sectional study describing factors associated with utilisation of GP services by a cohort of people who inject drugs.

Authors:  Dhanya Nambiar; Mark Stoové; Paul Dietze
Journal:  BMC Health Serv Res       Date:  2014-07-16       Impact factor: 2.655

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