Background: Many infectious and noninfectious triggers lead to inflammation of the vagina. Aim: We investigated the prevalence of causative vaginitis microorganisms in 516 pregnant and nonpregnant female volunteers. Vaginal samples were examined microscopically, cultured and tested for different pathogens. Results: Of the participants, 310 (60.1%) were pregnant, whereas 206 (39.9%) were nonpregnant. Using Amsel's criteria and Nugent's scores, bacterial vaginosis (BV) was diagnosed in 59.1%, and the prevalence of vulvovaginal candidiasis (VVC) was 50.2% in the population. Candida infections were significantly higher in nonpregnant females (p value ≤ 0.01), and 24% of females had mixed infections. The most common mixed infection was BV and Candida spp., detected in 21% of the cases. Conclusions: Bacterial vaginosis is the most common cause of vaginitis. We observed that 24% of females experienced mixed infections, and Candida albicans was the most common fungal species causing VVC. Trichomonas vaginalis prevalence was underestimated using wet mounts.
Background: Many infectious and noninfectious triggers lead to inflammation of the vagina. Aim: We investigated the prevalence of causative vaginitis microorganisms in 516 pregnant and nonpregnant female volunteers. Vaginal samples were examined microscopically, cultured and tested for different pathogens. Results: Of the participants, 310 (60.1%) were pregnant, whereas 206 (39.9%) were nonpregnant. Using Amsel's criteria and Nugent's scores, bacterial vaginosis (BV) was diagnosed in 59.1%, and the prevalence of vulvovaginal candidiasis (VVC) was 50.2% in the population. Candida infections were significantly higher in nonpregnant females (p value ≤ 0.01), and 24% of females had mixed infections. The most common mixed infection was BV and Candida spp., detected in 21% of the cases. Conclusions: Bacterial vaginosis is the most common cause of vaginitis. We observed that 24% of females experienced mixed infections, and Candida albicans was the most common fungal species causing VVC. Trichomonas vaginalis prevalence was underestimated using wet mounts.
Authors: Mark A Klebanoff; Jane R Schwebke; Jun Zhang; Tonja R Nansel; Kai-Fun Yu; William W Andrews Journal: Obstet Gynecol Date: 2004-08 Impact factor: 7.661
Authors: Maha Abdul-Aziz; Mohammed A K Mahdy; Rashad Abdul-Ghani; Nuha A Alhilali; Leena K A Al-Mujahed; Salma A Alabsi; Fatima A M Al-Shawish; Noura J M Alsarari; Wala Bamashmos; Shahad J H Abdulwali; Mahdi Al Karawani; Abdullah A Almikhlafy Journal: BMC Infect Dis Date: 2019-10-22 Impact factor: 3.090
Authors: Elizabeth A Torrone; Charles S Morrison; Pai-Lien Chen; Cynthia Kwok; Suzanna C Francis; Richard J Hayes; Katharine J Looker; Sheena McCormack; Nuala McGrath; Janneke H H M van de Wijgert; Deborah Watson-Jones; Nicola Low; Sami L Gottlieb Journal: PLoS Med Date: 2018-02-27 Impact factor: 11.069