Literature DB >> 28927765

Recurrent vulvovaginal candidiasis.

Freida Blostein1, Elizabeth Levin-Sparenberg1, Julian Wagner2, Betsy Foxman3.   

Abstract

PURPOSE: Recurrent vulvovaginal candidiasis (RVVC), multiple episodes of vulvovaginal candidiasis (VVC; vaginal yeast infection) within a 12-month period, adversely affects quality of life, mental health, and sexual activity. Diagnosis is not straightforward, as VVC is defined by the combination of often nonspecific vaginal symptoms and the presence of yeast-which is a common vaginal commensal. Estimating the incidence and prevalence is challenging: most VVC is diagnosed and treated empirically, the availability for purchase of effective therapies over the counter enables self-diagnosis and treatment, and the duration of the relatively benign VVC symptoms is short, introducing errors into any estimates relying on medical records or patient recall.
METHODS: We evaluate current estimates of VVC and RVVC and provide new prevalence estimates using data from a 2011 seven-country (n = 7345) internet panel survey on VVC conducted by Ipsos Health (https://www.ipsos.com/en). We also evaluate information on VVC-associated visits using the National Ambulatory Medical Care Survey.
RESULTS: The estimated probability of VVC by age 50 varied widely by country (from 23% to 49%, mean 39%), as did the estimated probability of RVVC after VVC (from 14% to 28%, mean 23%).
CONCLUSIONS: However estimated, the probability of RVVC was high suggesting RVVC is a common condition.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Diagnosis; Incidence; Prevalence; Recurrent; Vulvovaginal candidiasis

Mesh:

Substances:

Year:  2017        PMID: 28927765     DOI: 10.1016/j.annepidem.2017.08.010

Source DB:  PubMed          Journal:  Ann Epidemiol        ISSN: 1047-2797            Impact factor:   3.797


  26 in total

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3.  Brazilian Protocol for Sexually Transmitted Infections, 2020: infections causing vaginal discharge.

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4.  Vulvovaginal candidiasis and current perspectives: new risk factors and laboratory diagnosis by using MALDI TOF for identifying species in primary infection and recurrence.

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Review 5.  Animal Models and Alternatives in Vaginal Research: a Comparative Review.

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Review 7.  Healthy Vaginal Microbiota and Influence of Probiotics Across the Female Life Span.

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8.  Biofilm Formation of Candida albicans Facilitates Fungal Infiltration and Persister Cell Formation in Vaginal Candidiasis.

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Review 9.  It Takes Two to Tango: How a Dysregulation of the Innate Immunity, Coupled With Candida Virulence, Triggers VVC Onset.

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10.  Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.

Authors:  Priya Uppuluri; Shakti Singh; Abdullah Alqarihi; Clint S Schmidt; John P Hennessey; Michael R Yeaman; Scott G Filler; John E Edwards; Ashraf S Ibrahim
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