Literature DB >> 35966380

Necrotizing Soft Tissue Infections of the Perineum.

Bryan P Kline1, Nimalan A Jeganathan2.   

Abstract

Necrotizing soft tissue infections of the perineum are rapidly progressing infections associated with significant morbidity and mortality. Prompt diagnosis and management with early surgical debridement is necessary to improve survival from this deadly disease. Repeat debridements are not uncommon. Important adjuncts to surgery include broad-spectrum antibiotics and management in an intensive care unit, as patients frequently develop multisystem organ failure. Once the acute phase is managed, fecal diversion with either an ostomy or fecal management catheter can be considered to decrease soiling of the wound and facilitate healing. Long-term management requires meticulous wound care, often with the assistance of negative pressure wound therapy. Patients may ultimately require skin grafts or tissue flaps for soft tissue coverage following extensive surgical debridements. Thieme. All rights reserved.

Entities:  

Keywords:  Fournier's gangrene; necrotizing soft tissue infection; surgical debridement

Year:  2022        PMID: 35966380      PMCID: PMC9374531          DOI: 10.1055/s-0041-1740102

Source DB:  PubMed          Journal:  Clin Colon Rectal Surg        ISSN: 1530-9681


  49 in total

1.  Hyperbaric oxygen therapy for necrotizing fasciitis reduces mortality and the need for debridements.

Authors:  J A Riseman; W A Zamboni; A Curtis; D R Graham; H R Konrad; D S Ross
Journal:  Surgery       Date:  1990-11       Impact factor: 3.982

2.  A novel approach for the application of the vacuum assisted closure device to the difficult anatomy.

Authors:  Michael Fitzmaurice; Dot Lawson; Harold Friedman
Journal:  J Plast Reconstr Aesthet Surg       Date:  2006-06-06       Impact factor: 2.740

3.  Use of a Vacuum-Assisted Device for Fournier's Gangrene: A New Paradigm.

Authors:  Jonathan Silberstein; Julia Grabowski; J Kellog Parsons
Journal:  Rev Urol       Date:  2008

4.  Antibiotic effects on bacterial viability, toxin production, and host response.

Authors:  D L Stevens; A E Bryant; S P Hackett
Journal:  Clin Infect Dis       Date:  1995-06       Impact factor: 9.079

5.  Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America.

Authors:  Dennis L Stevens; Alan L Bisno; Henry F Chambers; E Patchen Dellinger; Ellie J C Goldstein; Sherwood L Gorbach; Jan V Hirschmann; Sheldon L Kaplan; Jose G Montoya; James C Wade
Journal:  Clin Infect Dis       Date:  2014-06-18       Impact factor: 9.079

6.  Clinical efficacy of polyspecific intravenous immunoglobulin therapy in patients with streptococcal toxic shock syndrome: a comparative observational study.

Authors:  Anna Linnér; Jessica Darenberg; Jan Sjölin; Birgitta Henriques-Normark; Anna Norrby-Teglund
Journal:  Clin Infect Dis       Date:  2014-06-13       Impact factor: 9.079

7.  A multicenter, retrospective study to evaluate the effect of preoperative stoma site marking on stomal and peristomal complications.

Authors:  Zehra Gocmen Baykara; Sevil Guler Demir; Ayise Karadag; Deniz Harputlu; Aysel Kahraman; Sercan Karadag; Aysel Oren Hin; Eylem Togluk; Meral Altinsoy; Sonca Erdem; Rabia Cihan
Journal:  Ostomy Wound Manage       Date:  2014-05       Impact factor: 2.629

8.  The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections.

Authors:  Chin-Ho Wong; Lay-Wai Khin; Kien-Seng Heng; Kok-Chai Tan; Cheng-Ooi Low
Journal:  Crit Care Med       Date:  2004-07       Impact factor: 7.598

9.  Necrotising soft tissue infections: the effect of hyperbaric oxygen on mortality.

Authors:  B Devaney; G Frawley; L Frawley; D V Pilcher
Journal:  Anaesth Intensive Care       Date:  2015-11       Impact factor: 1.669

Review 10.  World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections.

Authors:  Massimo Sartelli; Mark A Malangoni; Addison K May; Pierluigi Viale; Lillian S Kao; Fausto Catena; Luca Ansaloni; Ernest E Moore; Fred A Moore; Andrew B Peitzman; Raul Coimbra; Ari Leppaniemi; Yoram Kluger; Walter Biffl; Kaoru Koike; Massimo Girardis; Carlos A Ordonez; Mario Tavola; Miguel Cainzos; Salomone Di Saverio; Gustavo P Fraga; Igor Gerych; Michael D Kelly; Korhan Taviloglu; Imtiaz Wani; Sanjay Marwah; Miklosh Bala; Wagih Ghnnam; Nissar Shaikh; Osvaldo Chiara; Mario Paulo Faro; Gerson Alves Pereira; Carlos Augusto Gomes; Federico Coccolini; Cristian Tranà; Davide Corbella; Pietro Brambillasca; Yunfeng Cui; Helmut A Segovia Lohse; Vladimir Khokha; Kenneth Yy Kok; Suk-Kyung Hong; Kuo-Ching Yuan
Journal:  World J Emerg Surg       Date:  2014-11-18       Impact factor: 5.469

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