Literature DB >> 35951038

[Monotherapy with immune checkpoint blockade leads to clinical complete remission in patients with rectal cancer and microsatellite instability].

Markus Diefenhardt1, Emmanouil Fokas1, Claus Rödel2.   

Abstract

Entities:  

Year:  2022        PMID: 35951038     DOI: 10.1007/s00066-022-01990-7

Source DB:  PubMed          Journal:  Strahlenther Onkol        ISSN: 0179-7158            Impact factor:   4.033


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  7 in total

1.  Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

Authors:  Dung T Le; Jennifer N Durham; Kellie N Smith; Hao Wang; Bjarne R Bartlett; Laveet K Aulakh; Steve Lu; Holly Kemberling; Cara Wilt; Brandon S Luber; Fay Wong; Nilofer S Azad; Agnieszka A Rucki; Dan Laheru; Ross Donehower; Atif Zaheer; George A Fisher; Todd S Crocenzi; James J Lee; Tim F Greten; Austin G Duffy; Kristen K Ciombor; Aleksandra D Eyring; Bao H Lam; Andrew Joe; S Peter Kang; Matthias Holdhoff; Ludmila Danilova; Leslie Cope; Christian Meyer; Shibin Zhou; Richard M Goldberg; Deborah K Armstrong; Katherine M Bever; Amanda N Fader; Janis Taube; Franck Housseau; David Spetzler; Nianqing Xiao; Drew M Pardoll; Nickolas Papadopoulos; Kenneth W Kinzler; James R Eshleman; Bert Vogelstein; Robert A Anders; Luis A Diaz
Journal:  Science       Date:  2017-06-08       Impact factor: 47.728

2.  PD-1 Blockade in Mismatch Repair-Deficient, Locally Advanced Rectal Cancer.

Authors:  Andrea Cercek; Melissa Lumish; Jenna Sinopoli; Jill Weiss; Jinru Shia; Michelle Lamendola-Essel; Imane H El Dika; Neil Segal; Marina Shcherba; Ryan Sugarman; Zsofia Stadler; Rona Yaeger; J Joshua Smith; Benoit Rousseau; Guillem Argiles; Miteshkumar Patel; Avni Desai; Leonard B Saltz; Maria Widmar; Krishna Iyer; Janie Zhang; Nicole Gianino; Christopher Crane; Paul B Romesser; Emmanouil P Pappou; Philip Paty; Julio Garcia-Aguilar; Mithat Gonen; Marc Gollub; Martin R Weiser; Kurt A Schalper; Luis A Diaz
Journal:  N Engl J Med       Date:  2022-06-05       Impact factor: 176.079

3.  Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study.

Authors:  Luis A Diaz; Kai-Keen Shiu; Tae-Won Kim; Benny Vittrup Jensen; Lars Henrik Jensen; Cornelis Punt; Denis Smith; Rocio Garcia-Carbonero; Manuel Benavides; Peter Gibbs; Christelle de la Fourchardiere; Fernando Rivera; Elena Elez; Dung T Le; Takayuki Yoshino; Wen Yan Zhong; David Fogelman; Patricia Marinello; Thierry Andre
Journal:  Lancet Oncol       Date:  2022-04-12       Impact factor: 54.433

4.  Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

Authors:  Lorenzo F Fanchi; Krijn K Dijkstra; José G Van den Berg; Emile E Voest; John B Haanen; Myriam Chalabi; Arend G Aalbers; Karolina Sikorska; Marta Lopez-Yurda; Cecile Grootscholten; Geerard L Beets; Petur Snaebjornsson; Monique Maas; Marjolijn Mertz; Vivien Veninga; Gergana Bounova; Annegien Broeks; Regina G Beets-Tan; Thomas R de Wijkerslooth; Anja U van Lent; Hendrik A Marsman; Elvira Nuijten; Niels F Kok; Maria Kuiper; Wieke H Verbeek; Marleen Kok; Monique E Van Leerdam; Ton N Schumacher
Journal:  Nat Med       Date:  2020-04-06       Impact factor: 53.440

5.  Complete Pathological Response After Neoadjuvant Short-Course Immunotherapy with Ipilimumab and Nivolumab in Locally Advanced MSI-H/dMMR Rectal Cancer.

Authors:  Jörg Trojan; Sebastian Stintzing; Oliver Haase; Christine Koch; Paul Ziegler; Melanie Demes; Ivan Jelas
Journal:  Oncologist       Date:  2021-10-06

Review 6.  International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer.

Authors:  Emmanouil Fokas; Ane Appelt; Alexandra Gilbert; David Sebag-Montefiore; Claus Rödel; Robert Glynne-Jones; Geerard Beets; Rodrigo Perez; Julio Garcia-Aguilar; Eric Rullier; J Joshua Smith; Corrie Marijnen; Femke P Peters; Maxine van der Valk; Regina Beets-Tan; Arthur S Myint; Jean-Pierre Gerard; Simon P Bach; Michael Ghadimi; Ralf D Hofheinz; Krzysztof Bujko; Cihan Gani; Karin Haustermans; Bruce D Minsky; Ethan Ludmir; Nicholas P West; Maria A Gambacorta; Vincenzo Valentini; Marc Buyse; Andrew G Renehan
Journal:  Nat Rev Clin Oncol       Date:  2021-08-04       Impact factor: 66.675

7.  Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma.

Authors:  Rodabe N Amaria; Sangeetha M Reddy; Hussein A Tawbi; Michael A Davies; Merrick I Ross; Isabella C Glitza; Janice N Cormier; Carol Lewis; Wen-Jen Hwu; Ehab Hanna; Adi Diab; Michael K Wong; Richard Royal; Neil Gross; Randal Weber; Stephen Y Lai; Richard Ehlers; Jorge Blando; Denái R Milton; Scott Woodman; Robin Kageyama; Daniel K Wells; Patrick Hwu; Sapna P Patel; Anthony Lucci; Amy Hessel; Jeffrey E Lee; Jeffrey Gershenwald; Lauren Simpson; Elizabeth M Burton; Liberty Posada; Lauren Haydu; Linghua Wang; Shaojun Zhang; Alexander J Lazar; Courtney W Hudgens; Vancheswaran Gopalakrishnan; Alexandre Reuben; Miles C Andrews; Christine N Spencer; Victor Prieto; Padmanee Sharma; James Allison; Michael T Tetzlaff; Jennifer A Wargo
Journal:  Nat Med       Date:  2018-10-08       Impact factor: 53.440

  7 in total

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