Literature DB >> 35941364

Untangling the web of intratumour heterogeneity.

Zheqi Li1,2,3, Marco Seehawer1,2,3, Kornelia Polyak4,5,6.   

Abstract

Intratumour heterogeneity (ITH) is a hallmark of cancer that drives tumour evolution and disease progression. Technological and computational advances have enabled us to assess ITH at unprecedented depths, yet this accumulating knowledge has not had a substantial clinical impact. This is in part due to a limited understanding of the functional relevance of ITH and the inadequacy of preclinical experimental models to reproduce it. Here, we discuss progress made in these areas and illuminate future directions.
© 2022. Springer Nature Limited.

Entities:  

Mesh：

Year:  2022        PMID： 35941364     DOI： 10.1038/s41556-022-00969-x

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.213


  128 in total

Review 1.  Non-genetic mechanisms of therapeutic resistance in cancer.

Authors:  Jean-Christophe Marine; Sarah-Jane Dawson; Mark A Dawson
Journal:  Nat Rev Cancer       Date:  2020-10-08       Impact factor: 60.716

Review 2.  SMARCA family of genes.

Authors:  Runjan Chetty; Stefano Serra
Journal:  J Clin Pathol       Date:  2020-05       Impact factor: 3.411

3.  Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisions.

Authors:  Cristian Tomasetti; Bert Vogelstein
Journal:  Science       Date:  2015-01-02       Impact factor: 47.728

4.  Developmental chromatin programs determine oncogenic competence in melanoma.

Authors:  Arianna Baggiolini; Scott J Callahan; Lorenz Studer; Richard M White; Emily Montal; Joshua M Weiss; Tuan Trieu; Mohita M Tagore; Sam E Tischfield; Ryan M Walsh; Shruthy Suresh; Yujie Fan; Nathaniel R Campbell; Sarah C Perlee; Nathalie Saurat; Miranda V Hunter; Theresa Simon-Vermot; Ting-Hsiang Huang; Yilun Ma; Travis Hollmann; Satish K Tickoo; Barry S Taylor; Ekta Khurana; Richard P Koche
Journal:  Science       Date:  2021-09-03       Impact factor: 63.714

Review 5.  Cancer evolution: Darwin and beyond.

Authors:  Roberto Vendramin; Kevin Litchfield; Charles Swanton
Journal:  EMBO J       Date:  2021-08-30       Impact factor: 14.012

6.  Emergence of a High-Plasticity Cell State during Lung Cancer Evolution.

Authors:  Nemanja Despot Marjanovic; Matan Hofree; Jason E Chan; David Canner; Katherine Wu; Marianna Trakala; Griffin G Hartmann; Olivia C Smith; Jonathan Y Kim; Kelly Victoria Evans; Anna Hudson; Orr Ashenberg; Caroline B M Porter; Alborz Bejnood; Ayshwarya Subramanian; Kenneth Pitter; Yan Yan; Toni Delorey; Devan R Phillips; Nisargbhai Shah; Ojasvi Chaudhary; Alexander Tsankov; Travis Hollmann; Natasha Rekhtman; Pierre P Massion; John T Poirier; Linas Mazutis; Ruifang Li; Joo-Hyeon Lee; Angelika Amon; Charles M Rudin; Tyler Jacks; Aviv Regev; Tuomas Tammela
Journal:  Cancer Cell       Date:  2020-07-23       Impact factor: 31.743

7.  Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung.

Authors:  Sai Ma; Lindsay M LaFave; Arjun Bhutkar; Carla P Concepcion; Manyuan Liu; Lydia P DeAngelo; Jonathan Y Kim; Isabella Del Priore; Adam J Schoenfeld; Manon Miller; Vinay K Kartha; Peter M K Westcott; Francisco J Sánchez-Rivera; Kevin Meli; Manav Gupta; Roderick T Bronson; Gregory J Riely; Natasha Rekhtman; Charles M Rudin; Carla F Kim; Aviv Regev; Jason D Buenrostro; Tyler Jacks
Journal:  Cancer Discov       Date:  2021-09-24       Impact factor: 38.272

8.  Differentiation-state plasticity is a targetable resistance mechanism in basal-like breast cancer.

Authors:  Tyler Risom; Ellen M Langer; Margaret P Chapman; Juha Rantala; Andrew J Fields; Christopher Boniface; Mariano J Alvarez; Nicholas D Kendsersky; Carl R Pelz; Katherine Johnson-Camacho; Lacey E Dobrolecki; Koei Chin; Anil J Aswani; Nicholas J Wang; Andrea Califano; Michael T Lewis; Claire J Tomlin; Paul T Spellman; Andrew Adey; Joe W Gray; Rosalie C Sears
Journal:  Nat Commun       Date:  2018-09-19       Impact factor: 14.919

9.  Distinct initiating events underpin the immune and metabolic heterogeneity of KRAS-mutant lung adenocarcinoma.

Authors:  Sarah A Best; Sheryl Ding; Ariena Kersbergen; Xueyi Dong; Ji-Ying Song; Yi Xie; Boris Reljic; Kaiming Li; James E Vince; Vivek Rathi; Gavin M Wright; Matthew E Ritchie; Kate D Sutherland
Journal:  Nat Commun       Date:  2019-09-13       Impact factor: 14.919

10.  Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma.

Authors:  Ruiping Wang; Minghao Dang; Kazuto Harada; Guangchun Han; Fang Wang; Melissa Pool Pizzi; Meina Zhao; Ghia Tatlonghari; Shaojun Zhang; Dapeng Hao; Yang Lu; Shuangtao Zhao; Brian D Badgwell; Mariela Blum Murphy; Namita Shanbhag; Jeannelyn S Estrella; Sinchita Roy-Chowdhuri; Ahmed Adel Fouad Abdelhakeem; Yuanxin Wang; Guang Peng; Samir Hanash; George A Calin; Xingzhi Song; Yanshuo Chu; Jianhua Zhang; Mingyao Li; Ken Chen; Alexander J Lazar; Andrew Futreal; Shumei Song; Jaffer A Ajani; Linghua Wang
Journal:  Nat Med       Date:  2021-01-04       Impact factor: 53.440
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.