Matthias Gräser1,2, Franz Wegner3, Jonas Schumacher4, Mandy Ahlborg4, Ksenija Gräfe5, Eric Aderhold4, Yvonne Blancke Soares5, Kerstin Lüdtke-Buzug5, Alexander Neumann5, Pascal Stagge4,5, Huimin Wei5, Justin Ackers4, Thorsten M Buzug4,5. 1. Fraunhofer Einrichtung für Individualisierte und Zellbasierte Medizintechnik, Mönkhofer Weg 239a, 23562, Lübeck, Deutschland. matthias.graeser@imte.fraunhofer.de. 2. Institut für Medizintechnik, Universität zu Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland. matthias.graeser@imte.fraunhofer.de. 3. Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland. 4. Fraunhofer Einrichtung für Individualisierte und Zellbasierte Medizintechnik, Mönkhofer Weg 239a, 23562, Lübeck, Deutschland. 5. Institut für Medizintechnik, Universität zu Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Deutschland.
Abstract
BACKGROUND: Magnetic particle imaging offers far-reaching potential with a unique range of applications. OBJECTIVES: Identification of application scenarios with added value for clinical use. METHODS: Overview of previous application scenarios in phantom and small animal models, evaluation of dual-use potential. RESULTS: With its unique application profile, magnetic particle imaging offers a solution for clinical use where common, established imaging techniques reach their limits. As a tracer imaging technique, it is particularly characterized by its high speed, sensitivity and contrast-to-noise ratio. The low magnetic fields and low power consumption allow imaging to be mobile and taken to locations that were previously inaccessible. CONCLUSION: Magnetic particle imaging has seen rapid development in recent years. The applications demonstrated in the small animal model and phantom were able to support the versatility and added value of the method. With the availability of human imaging systems, the technology must face clinical verification studies.
BACKGROUND: Magnetic particle imaging offers far-reaching potential with a unique range of applications. OBJECTIVES: Identification of application scenarios with added value for clinical use. METHODS: Overview of previous application scenarios in phantom and small animal models, evaluation of dual-use potential. RESULTS: With its unique application profile, magnetic particle imaging offers a solution for clinical use where common, established imaging techniques reach their limits. As a tracer imaging technique, it is particularly characterized by its high speed, sensitivity and contrast-to-noise ratio. The low magnetic fields and low power consumption allow imaging to be mobile and taken to locations that were previously inaccessible. CONCLUSION: Magnetic particle imaging has seen rapid development in recent years. The applications demonstrated in the small animal model and phantom were able to support the versatility and added value of the method. With the availability of human imaging systems, the technology must face clinical verification studies.
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