Literature DB >> 35896613

Spontaneous Motor Recovery after Cervical Spinal Cord Injury: Issues for Nerve Transfer Surgery Decision Making.

Jana Dengler1,2, John D Steeves3, Armin Curt4, Munish Mehra5, Christine B Novak2, Ida K Fox6,7.   

Abstract

STUDY
DESIGN: Retrospective cohort study.
OBJECTIVES: To quantify spontaneous upper extremity motor recovery between 6 and 12 months after spinal cord injury (SCI) to help guide timing of nerve transfer surgery to improve upper limb function in cervical SCI.
SETTING: Nineteen European SCI rehabilitation centers.
METHODS: Data was extracted from the European Multicenter Study of SCI database for individuals with mid-level cervical SCI (N = 268). Muscle function grades at 6 and 12 months post-SCI were categorized for analysis.
RESULTS: From 6 to 12 months after SCI, spontaneous surgically-relevant recovery was limited. Of all limbs (N = 263) with grade 0-2 elbow extension at 6 months, 4% regained grade 4-5 and 11% regained grade 3 muscle function at 12 months. Of all limbs (N = 380) with grade 0-2 finger flexion at 6 months, 3% regained grade 4-5 and 5% regained grade 3 muscle function at 12 months.
CONCLUSION: This information supports early (6 month) post-injury surgical consultation and evaluation. With this information, individuals with SCI can more fully engage in preference-based decision-making about surgical intervention versus continued rehabilitation and spontaneous recovery to gain elbow extension and/or hand opening and closing.
© 2022. The Author(s), under exclusive licence to International Spinal Cord Society.

Entities:  

Mesh:

Year:  2022        PMID: 35896613     DOI: 10.1038/s41393-022-00834-6

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.473


  28 in total

Review 1.  Plasticity of motor systems after incomplete spinal cord injury.

Authors:  O Raineteau; M E Schwab
Journal:  Nat Rev Neurosci       Date:  2001-04       Impact factor: 34.870

2.  Injured metamere and functional surgery of the tetraplegic upper limb.

Authors:  Bertrand Coulet; Yves Allieu; Michel Chammas
Journal:  Hand Clin       Date:  2002-08       Impact factor: 1.907

Review 3.  Current Best Peripheral Nerve Transfers for Spinal Cord Injury.

Authors:  Elspeth J R Hill; Ida K Fox
Journal:  Plast Reconstr Surg       Date:  2019-01       Impact factor: 4.730

4.  Expanding traditional tendon-based techniques with nerve transfers for the restoration of upper limb function in tetraplegia: a prospective case series.

Authors:  Natasha van Zyl; Bridget Hill; Catherine Cooper; Jodie Hahn; Mary P Galea
Journal:  Lancet       Date:  2019-07-04       Impact factor: 79.321

5.  Motor and sensory recovery following incomplete tetraplegia.

Authors:  R L Waters; R H Adkins; J S Yakura; I Sie
Journal:  Arch Phys Med Rehabil       Date:  1994-03       Impact factor: 3.966

6.  The Use of Nerve Transfers to Restore Upper Extremity Function in Cervical Spinal Cord Injury.

Authors:  Ida K Fox; Christine B Novak; Emily M Krauss; Gwendolyn M Hoben; Craig M Zaidman; Rimma Ruvinskaya; Neringa Juknis; Anke C Winter; Susan E Mackinnon
Journal:  PM R       Date:  2018-03-15       Impact factor: 2.298

7.  Contributing factors to poor functional recovery after delayed nerve repair: prolonged denervation.

Authors:  S Y Fu; T Gordon
Journal:  J Neurosci       Date:  1995-05       Impact factor: 6.167

8.  Recovery from a spinal cord injury: significance of compensation, neural plasticity, and repair.

Authors:  Armin Curt; Hubertus J A Van Hedel; Daniel Klaus; Volker Dietz
Journal:  J Neurotrauma       Date:  2008-06       Impact factor: 5.269

9.  Motor and sensory recovery following complete tetraplegia.

Authors:  R L Waters; R H Adkins; J S Yakura; I Sie
Journal:  Arch Phys Med Rehabil       Date:  1993-03       Impact factor: 3.966

10.  Lower Motor Neuron Abnormality in Chronic Cervical Spinal Cord Injury: Implications for Nerve Transfer Surgery.

Authors:  Michael J Berger; Lawrence Robinson; Emily M Krauss
Journal:  J Neurotrauma       Date:  2021-04-01       Impact factor: 5.269

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.