Literature DB >> 3585587

Prognostic significance of DNA aneuploidy and cell proliferation in rectal adenocarcinomas.

P Quirke, M F Dixon, A D Clayden, P Durdey, J E Dyson, N S Williams, C C Bird.   

Abstract

DNA content and cell proliferation were studied retrospectively in 125 patients presenting from 1974-1981 with rectal adenocarcinoma. The presence of DNA aneuploidy or a high level of cell proliferation were associated with a poor prognosis and when combined were the best predictor of survival after Dukes's stage excluding all other pathological assessments investigated. High cell turnover was significantly associated with an infiltrative pattern of growth, an observation that might explain the poorer prognosis of this pattern in rectal adenocarcinomas.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3585587     DOI： 10.1002/path.1711510408

Source DB:  PubMed          Journal:  J Pathol        ISSN： 0022-3417            Impact factor:   7.996


  37 in total

1.  Comparison of deoxyribonucleic acid ploidy and nuclear expressed p62 c-myc oncogene in the prognosis of colorectal cancer.

Authors:  S Rowley; K M Newbold; J Gearty; M R Keighley; I A Donovan; J P Neoptolemos
Journal:  World J Surg       Date:  1990 Jul-Aug       Impact factor: 3.352

Review 2.  Anastomosis or stoma for low rectal cancer?

Authors:  C Hall; S Rowley; J P Neoptolemos
Journal:  Postgrad Med J       Date:  1989-03       Impact factor: 2.401

3.  [DNA cytophotometry in pathology and surgery].

Authors:  M Dietel
Journal:  Langenbecks Arch Chir       Date:  1992

Review 4.  Genetics of colon cancer.

Authors:  D J Ahnen
Journal:  West J Med       Date:  1991-06

5.  Flow cytometric analysis in colorectal carcinoma: prognostic significance of cellular DNA content.

Authors:  A Schillaci; D D Tirindelli; M Ferri; L Teodori; F Mauro; V Nicolanti; S Stipa
Journal:  Int J Colorectal Dis       Date:  1990-12       Impact factor: 2.571

6.  Flow cytometry in colon cancer: does flow cytometric cell cycle analysis help predict for short-term recurrence in patients with colorectal carcinoma?

Authors:  C Hixon; J Furlong; A Silbergleit
Journal:  J Natl Med Assoc       Date:  1995-11       Impact factor: 1.798

Review 7.  Review: assessment of cell proliferation in histological material.

Authors:  P A Hall; D A Levison
Journal:  J Clin Pathol       Date:  1990-03       Impact factor: 3.411

8.  Tumor DNA content in resectable, primary colorectal carcinoma.

Authors:  W A Kokal; R L Gardine; K Sheibani; P L Morris; E Prager; I W Zak; J J Terz
Journal:  Ann Surg       Date:  1989-02       Impact factor: 12.969

9.  Clinical importance of DNA content in rectal cancer measured by flow cytometry.

Authors:  J R Jass; K Mukawa; H S Goh; S B Love; D Capellaro
Journal:  J Clin Pathol       Date:  1989-03       Impact factor: 3.411

10.  Prognostic significance of tumor markers in colorectal cancer patients: DNA index, S-phase fraction, p53 expression, and Ki-67 index.

Authors:  Y T Chen; M J Henk; K J Carney; W D Wong; D A Rothenberger; T Zheng; M Feygin; R D Madoff
Journal:  J Gastrointest Surg       Date:  1997 May-Jun       Impact factor: 3.452
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.