Literature DB >> 35854006

Long non-coding RNAs: a valuable biomarker for metabolic syndrome.

Mohammad Rashidmayvan1, Reza Sahebi2, Majid Ghayour-Mobarhan3.   

Abstract

Long non-coding RNAs (lncRNAs) have become important regulators of gene expression because they affect a wide range of biological processes, such as cell growth, death, differentiation, and aging. More and more evidence suggests that lncRNAs play a role in maintaining metabolic homeostasis. When certain lncRNAs are out of balance, metabolic disorders like diabetes, obesity, and heart disease get worse. In this review, we talk about what we know about how lncRNAs control metabolism, with a focus on diseases caused by long-term inflammation and the characteristics of the metabolic syndrome. We looked at lncRNAs and their molecular targets in the pathogenesis of signaling pathways. We also talked about how lncRNAs are becoming more and more interesting as diagnostic and therapeutic targets for improving metabolic homeostasis.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Hypertension; Insulin resistance; Long noncoding RNA; Metabolic syndrome

Mesh:

Substances:

Year:  2022        PMID: 35854006     DOI: 10.1007/s00438-022-01922-1

Source DB:  PubMed          Journal:  Mol Genet Genomics        ISSN: 1617-4623            Impact factor:   2.980


  99 in total

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Review 8.  MALAT1 as a Diagnostic and Therapeutic Target in Diabetes-Related Complications: A Promising Long-Noncoding RNA.

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10.  Circulating long noncoding RNA GAS5 levels are correlated to prevalence of type 2 diabetes mellitus.

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Journal:  BBA Clin       Date:  2015-09-11
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