Literature DB >> 35846397

Implant-related complications in patients with opioid use disorder undergoing primary shoulder arthroplasties: a matched-controlled analysis.

Samuel J Swiggett1, Matthew L Ciminero1, Miriam D Weisberg1, Rushabh M Vakharia1, Ramin Sadeghpour1, Jack Choueka1.   

Abstract

Background: The purpose of this study was to investigate whether patients undergoing primary shoulder arthroplasty with opioid use disorder have higher rates of (1) implant-related complications; (2) in-hospital lengths of stay; (3) readmission rates; and (4) costs of care.
Methods: Opioid use disorder patients undergoing primary shoulder arthroplasty were queried and matched in a 1:5 ratio to controls by age, sex, and medical comorbidities within the Medicare database. The query yielded 25,489 patients with (n = 4253) and without (n = 21,236) opioid use disorder. Primary outcomes analyzed included: 2-year implant related complications, in-hospital lengths of stay, 90-day readmission rates, and 90-day costs of care. A p value less than 0.01 was considered statistically significant.
Results: Opioid use disorder patients had significantly longer in-hospital lengths of stay (3 days vs. 2 days; p < 0.0001) compared to matched controls. Opioid use disorder patients were also found to have higher incidence and odds (OR) of readmission rates (12.84 vs. 7.45%; OR: 1.16, p < 0.0001) and implant-related complications (20.03 vs. 7.95%; OR: 1.82, p < 0.0001). Study group patients also incurred significantly higher 90-day costs of care ($16,918.85 vs. $15,195.37, p < 0.0001). Discussion: This study can be used to help further augment efforts to reduce opioid prescriptions from healthcare providers in shoulder arthroplasty settings.
© 2021 The British Elbow & Shoulder Society.

Entities:  

Keywords:  Opioid use disorder; complications; costs medicare; readmissions; shoulder arthroplasty

Year:  2021        PMID: 35846397      PMCID: PMC9284306          DOI: 10.1177/1758573221994790

Source DB:  PubMed          Journal:  Shoulder Elbow        ISSN: 1758-5732


  38 in total

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Authors:  Sunny H Kim; Barton L Wise; Yuqing Zhang; Robert M Szabo
Journal:  J Bone Joint Surg Am       Date:  2011-12-21       Impact factor: 5.284

Review 2.  Opioids and HIV/HCV infection.

Authors:  Xu Wang; Ting Zhang; Wen-Zhe Ho
Journal:  J Neuroimmune Pharmacol       Date:  2011-07-14       Impact factor: 4.147

3.  Psychotropic medications and the risk of fracture: a meta-analysis.

Authors:  Bahi Takkouche; Agustín Montes-Martínez; Sudeep S Gill; Mahyar Etminan
Journal:  Drug Saf       Date:  2007       Impact factor: 5.606

Review 4.  Non-analgesic effects of opioids: the interaction of opioids with bone and joints.

Authors:  Consalvo Mattia; Eleonora Di Bussolo; Flaminia Coluzzi
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

5.  Elective Shoulder Surgery in the Opioid Naïve: Rates of and Risk Factors for Long-term Postoperative Opioid Use.

Authors:  Timothy S Leroux; Bryan M Saltzman; Shelby A Sumner; Naomi Maldonado-Rodriguez; Avinesh Agarwalla; Bheeshma Ravi; Gregory L Cvetanovich; Christian J Veillette; Nikhil N Verma; Anthony A Romeo
Journal:  Am J Sports Med       Date:  2019-04       Impact factor: 6.202

6.  Preoperative Opioid Misuse is Associated With Increased Morbidity and Mortality After Elective Orthopaedic Surgery.

Authors:  Mariano E Menendez; David Ring; Brian T Bateman
Journal:  Clin Orthop Relat Res       Date:  2015-02-19       Impact factor: 4.176

7.  Morphine inhibition of lymphocyte activity is mediated by an opioid dependent mechanism.

Authors:  B M Bayer; S Daussin; M Hernandez; L Irvin
Journal:  Neuropharmacology       Date:  1990-04       Impact factor: 5.250

8.  Opioid prescriptions for chronic pain and overdose: a cohort study.

Authors:  Kate M Dunn; Kathleen W Saunders; Carolyn M Rutter; Caleb J Banta-Green; Joseph O Merrill; Mark D Sullivan; Constance M Weisner; Michael J Silverberg; Cynthia I Campbell; Bruce M Psaty; Michael Von Korff
Journal:  Ann Intern Med       Date:  2010-01-19       Impact factor: 25.391

9.  Trends in cervical disc arthroplasty and revisions in the Medicare database.

Authors:  Timothy R Niedzielak; Bijan J Ameri; Blaze Emerson; Rushabh M Vakharia; Martin W Roche; John P Malloy
Journal:  J Spine Surg       Date:  2018-09

10.  Healthcare costs and utilization associated with high-risk prescription opioid use: a retrospective cohort study.

Authors:  Hsien-Yen Chang; Hadi Kharrazi; Dave Bodycombe; Jonathan P Weiner; G Caleb Alexander
Journal:  BMC Med       Date:  2018-05-16       Impact factor: 8.775

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