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Literature DB >> 22747537

Non-analgesic effects of opioids: the interaction of opioids with bone and joints.

Consalvo Mattia¹, Eleonora Di Bussolo, Flaminia Coluzzi.

Abstract

Opioid consumption is associated with a wide range of side effects. Potential interference of opioids with bone and joint activity has emerged in the last few years. Opioids increase the risk of fracture, especially in elderly patients. Moreover, opioids interfere with the endocrine system, and their chronic use is a recognized risk factor for osteoporosis. Pathogenetic mechanisms at the basis of the interference of opioids with bones and joints are analysed in this review.

Entities: Disease Species

Mesh：

Substances：
Analgesics, Opioid

Year: 2012 PMID： 22747537 DOI： 10.2174/138161212803582487

Source DB: PubMed Journal: Curr Pharm Des ISSN： 1381-6128 Impact factor: 3.116

Keyword Cloud
Cited

12 in total

Review 1. Implications of analgesics use in osteoporotic-related pain treatment: focus on opioids.

Authors: Renato Vellucci; Consalvo Mattia; Ludovica Celidonio; Rocco Domenico Mediati
Journal: Clin Cases Miner Bone Metab Date: 2016-10-05

Review 2. Bone pain mechanism in osteoporosis: a narrative review.

Authors: Consalvo Mattia; Flaminia Coluzzi; Ludovica Celidonio; Renato Vellucci
Journal: Clin Cases Miner Bone Metab Date: 2016-10-05

3. Height-corrected low bone density associates with severe outcomes in sickle cell disease: SCCRIP cohort study results.

Authors: Oyebimpe O Adesina; James G Gurney; Guolian Kang; Martha Villavicencio; Jason R Hodges; Wassim Chemaitilly; Sue C Kaste; Babette S Zemel; Jane S Hankins
Journal: Blood Adv Date: 2019-05-14

4. Implant-related complications in patients with opioid use disorder undergoing primary shoulder arthroplasties: a matched-controlled analysis.

Authors: Samuel J Swiggett; Matthew L Ciminero; Miriam D Weisberg; Rushabh M Vakharia; Ramin Sadeghpour; Jack Choueka
Journal: Shoulder Elbow Date: 2021-03-02

Non-analgesic effects of opioids: the interaction of opioids with bone and joints.

Review 1. Implications of analgesics use in osteoporotic-related pain treatment: focus on opioids.

Review 2. Bone pain mechanism in osteoporosis: a narrative review.

3. Height-corrected low bone density associates with severe outcomes in sickle cell disease: SCCRIP cohort study results.

4. Implant-related complications in patients with opioid use disorder undergoing primary shoulder arthroplasties: a matched-controlled analysis.

5. Herpes zoster and the risks of osteoporosis and fracture: a nationwide cohort study.

6. Sensitivity of quantitative sensory models to morphine analgesia in humans.

7. The unsolved case of "bone-impairing analgesics": the endocrine effects of opioids on bone metabolism.

Review 8. Opioid therapy pharmacogenomics for noncancer pain: efficacy, adverse events, and costs.

9. Association Between Commonly Prescribed Opioids and Androgen Deficiency in Men: A Retrospective Cohort Analysis.

Review 10. Testosterone deficiency in non-cancer opioid-treated patients.