| Literature DB >> 35838975 |
Krist Helen Antunes1, Ana Paula Duarte de Souza2.
Abstract
The use of in vitro methods of infecting cell lines to test new treatments for SARS-CoV-2 does not always recapitulate the real context of the infection, and mouse models for SARS-CoV-2 infection are limited. Here we describe a novel ex vivo approach by collecting, isolating, and culturing nasal epithelial cells obtained from patients with COVID-19. This technique allows us to study immune responses and test new treatments directly on cells from patients naturally infected with SARS-CoV-2.Entities:
Keywords: COVID-19; Cell culture; Ex vivo; Isolation; Nasopharyngeal cells; SARS-CoV-2
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Year: 2022 PMID： 35838975 DOI： 10.1007/978-1-0716-2395-4_28
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745