Literature DB >> 35838531

Animal Models of Hepatocellular Carcinoma for Local-Regional Intraarterial Therapies.

Vishnu M Chandra1, Luke R Wilkins1, David L Brautigan1.   

Abstract

Animal models play a crucial role in developing and testing new therapies for hepatocellular carcinoma (HCC), providing preclinical evidence prior to exploring human safety and efficacy outcomes. The interventional radiologist must weigh the advantages and disadvantages of various animal models available when testing a new local-regional therapy. This review highlights the currently available animal models for testing local-regional therapies for HCC and details the importance of considering animal genetics, tumor biology, and molecular mechanisms when ultimately choosing an animal model. Keywords: Animal Studies, Interventional-Vascular, Molecular Imaging-Clinical Translation, Molecular Imaging-Cancer, Chemoembolization, Liver © RSNA, 2022.

Entities:  

Keywords:  Animal Studies; Chemoembolization; Interventional-Vascular; Liver; Molecular Imaging-Cancer; Molecular Imaging-Clinical Translation

Mesh：

Year:  2022        PMID： 35838531      PMCID： PMC9358488          DOI： 10.1148/rycan.210098

Source DB:  PubMed          Journal:  Radiol Imaging Cancer        ISSN： 2638-616X


  66 in total

1.  Development of an animal model for radiofrequency ablation of primary, virally induced hepatocellular carcinoma in the woodchuck.

Authors:  Charles T Burke; John M Cullen; Andrei State; Sashi Gadi; Kathy Wilber; Michael Rosenthal; Anna Bulysheva; Anthony Pease; Mathew A Mauro; Henry Fuchs
Journal:  J Vasc Interv Radiol       Date:  2011-09-29       Impact factor: 3.464

2.  Transarterial Chemoembolization in a Woodchuck Model of Hepatocellular Carcinoma.

Authors:  William F Pritchard; David L Woods; Juan A Esparza-Trujillo; Matthew F Starost; Michal Mauda-Havakuk; Andrew S Mikhail; Ivane Bakhutashvili; Shelby Leonard; Elizabeth C Jones; Venkatesh Krishnasamy; John W Karanian; Bradford J Wood
Journal:  J Vasc Interv Radiol       Date:  2020-02-24       Impact factor: 3.464

3.  TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma.

Authors:  Pengyuan Yang; Qi-Jing Li; Yuxiong Feng; Yun Zhang; Geoffrey J Markowitz; Shanglei Ning; Yuezhen Deng; Jiangsha Zhao; Shan Jiang; Yunfei Yuan; Hong-Yang Wang; Shu-Qun Cheng; Dong Xie; Xiao-Fan Wang
Journal:  Cancer Cell       Date:  2012-09-11       Impact factor: 31.743

4.  Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma.

Authors:  Terence P F Gade; Elizabeth Tucker; Michael S Nakazawa; Stephen J Hunt; Waihay Wong; Bryan Krock; Charles N Weber; Gregory J Nadolski; Timothy W I Clark; Michael C Soulen; Emma E Furth; Jeffrey D Winkler; Ravi K Amaravadi; M Celeste Simon
Journal:  Radiology       Date:  2017-03-02       Impact factor: 11.105

5.  Modified model of VX2 tumor overexpressing vascular endothelial growth factor.

Authors:  Florentina Pascale; Saida-Homayra Ghegediban; Michel Bonneau; Laurent Bedouet; Julien Namur; Valentin Verret; Isabelle Schwartz-Cornil; Michel Wassef; Alexandre Laurent
Journal:  J Vasc Interv Radiol       Date:  2012-04-11       Impact factor: 3.464

6.  Differential expression of angiogenesis-related miRNAs and VEGFA in cirrhosis and hepatocellular carcinoma.

Authors:  André R C P de Oliveira; Márcia M U Castanhole-Nunes; Patrícia M Biselli-Chicote; Érika C Pavarino; Rita de C M A da Silva; Renato F da Silva; Eny M Goloni-Bertollo
Journal:  Arch Med Sci       Date:  2020-08-10       Impact factor: 3.318

7.  Application of magnetic resonance imaging in transgenic and chemical mouse models of hepatocellular carcinoma.

Authors:  Julia Freimuth; Nikolaus Gassler; Nives Moro; Rolf W Günther; Christian Trautwein; Christian Liedtke; Gabriele A Krombach
Journal:  Mol Cancer       Date:  2010-04-29       Impact factor: 27.401

8.  Liver tumors: monitoring embolization in rabbits with VX2 tumors--transcatheter intraarterial first-pass perfusion MR imaging.

Authors:  Dingxin Wang; Affaan K Bangash; Thomas K Rhee; Gayle E Woloschak; Tatjana Paunesku; Riad Salem; Reed A Omary; Andrew C Larson
Journal:  Radiology       Date:  2007-10       Impact factor: 11.105

Review 9.  MicroRNAs in the Pathogenesis of Hepatocellular Carcinoma: A Review.

Authors:  Asahiro Morishita; Kyoko Oura; Tomoko Tadokoro; Koji Fujita; Joji Tani; Tsutomu Masaki
Journal:  Cancers (Basel)       Date:  2021-01-29       Impact factor: 6.639

10.  Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.

Authors: 
Journal:  Cell       Date:  2017-06-15       Impact factor: 66.850
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