| Literature DB >> 35821044 |
Srinivas Marmamula1,2,3,4, Thirupathi Reddy Kumbham5,6, Rahul Shidhaye7, Satya Brahmanandam Modepalli5,6, Navya Rekha Barrenkala5,6, Ratnakar Yellapragada5,6, Jill Keeffe5.
Abstract
We report prevalence and risk factors for multimorbidity and multi-disability among elderly people in residential care in the Hyderabad region in South India. In total, 1182 elderly (aged ≥ 60) participants were examined in 41 homes for the aged centres. Detailed interviews were conducted by trained personnel to collect personal and demographic information. A questionnaire was used to assess the history of non-communicable diseases and Washington Disability Questionnaire (WDQ) was administered to assess disabilities. The mean age of the participants was 75.0 years (SD 8.8 years; range: 60-108 years), 35.4% were men, 20.3% had no formal education, 60.7% had school education and 19% had higher education. The prevalence of multimorbidity was 37.6% (95% CI: 34.8-40.4). Prevalence of multi-disability was 23.6% (95% CI: 21.2-26.3; n = 270). In total, 857 (72.5%) participants reported using at least one medication for NCDs. Over a third of the elderly in residential care had multimorbidity, and a quarter of them had multi-disability. A holistic health care system that comprises health and wellness coupled with rehabilitation to address disabilities is needed to achieve healthy aging in elderly in homes for the aged in India.Entities:
Mesh:
Year: 2022 PMID: 35821044 PMCID: PMC9276822 DOI: 10.1038/s41598-022-15943-8
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.996
Association of multimorbidity (≥ 2 conditions) with sociodemographic and other characteristics (multiple logistic regression analysis).
| Total in the sample (n) | Participants with multimorbidity (n) | Prevalence (95% CI) | Crude odds ratio (95% CI)a | P value | Adjusted Odds ratio (95% CI)b | P value | |
|---|---|---|---|---|---|---|---|
| 60–69 | 329 | 113 | 34.3 (29.2–39.7) | Reference | Reference | ||
| 70–79 | 453 | 188 | 41.5 (36.9–46.2) | 1.36 (1.01–1.82) | 0.043 | 1.37 (1.01–1.86) | 0.04 |
| 80 and above | 400 | 143 | 35.8 (31.0–40.7) | 1.06 (0.78–1.44) | 0.70 | 1.13 (0.82–1.56) | 0.46 |
| Male | 418 | 145 | 34.7 (30.1–39.5) | Reference | Reference | ||
| Female | 764 | 299 | 39.1 (35.6–42.7) | 1.21 (0.94–1.55) | 0.131 | 1.40 (0.98–1.99) | 0.07 |
| Higher education | 225 | 82 | 36.4 (30.1–43.1) | Reference | Reference | ||
| School education | 717 | 282 | 39.3 (35.7–43.0) | 1.13 (0.83–1.54) | 0.44 | 1.15 (0.82–1.620) | 0.8 |
| No education | 240 | 80 | 33.3 (27.4–39.7) | 0.87 (0.60–1.28) | 0.48 | 1.06 (0.68–1.64) | 0.26 |
| Free home | 190 | 51 | 26.8 (20.7–33.7) | Reference | Reference | ||
| Subsidised home | 491 | 196 | 39.9 (35.4–44.4) | 1.81 (1.25–2.62) | < 0.01 | 1.73 (1.18–2.53) | 0.01 |
| Paid homes | 510 | 197 | 38.6 (34.4–43.0) | 1.77 (1.22–2.55) | < 0.01 | 1.79 (1.20–2.67) | < 0.01 |
| Never | 976 | 364 | 37.3 (34.2–40.3) | Reference | Reference | ||
| Current/past | 206 | 80 | 38.8 (32.1–45.9) | 1.07 (0.78–1.45) | 0.678 | 1.59 (1.04–2.43) | 0.03 |
| Never | 971 | 371 | 38.2 (35.1–41.3) | Reference | Reference | ||
| Current/past | 211 | 73 | 34.6 (28.2–41.4) | 0.86 (0.63–1.17) | 0.327 | 0.87 (0.60–1.28) | 0.49 |
| Normal/underweight (< 18.5–25) | 463 | 149 | 32.2 (27.9–36.6) | Reference | Reference | ||
| Overweight (> 25–30) | 310 | 147 | 47.4 (41.7–52.1) | 1.90 (1.41–2.56) | < 0.01 | 1.86 (1.37–2.52) | < 0.01 |
| Obese (> 30) | 156 | 73 | 46.8 (38.8–54.9) | 1.85 (1.28–2.68) | < 0.01 | 1.71 (1.16–2.51) | 0.01 |
| Missing data | 253 | 75 | 29.6 (24.1–35.7) | 0.89 (0.63–1.24) | 0.49 | 0.84 (0.60–1.19) | 0.33 |
aBased on simple logistic regression with multimorbidity as the outcome variable.
bBased on multiple logistic regression with multimorbidity as the outcome variable and the predictors entered at the same time.
Figure 1Prevalence of non-communicable diseases and multimorbidity stratified by gender (n = 1182); Statistical significance is shown in parenthesis (Chi squared test).
Prevalence of number of non-communicable diseases with 95% confidence intervals.
| Number of participants | Prevalence (95% CI) | |
|---|---|---|
| No NCD | 346 | 29. 3 (26.7–31.9) |
| One NCD | 392 | 33. 3 (30.5–36.0) |
| Two NCDs | 309 | 26.1 (23.7–28.7) |
| Three NCDs | 108 | 9.1 (7.6–10.9) |
| Four or more NCDs | 27 | 2.3 (1.5–3.3) |
Figure 2Prevalence of disabilities and multi-disability stratified by gender (n = 1140); statistical significance is shown in parenthesis (Chi squared test).
Association of multi-disability (≥ 2 conditions) with sociodemographic and other characteristics (multiple logistic regression analysis) ;
| Total in the sample (n) | Participants with multi-disability (n) | Prevalence (95% CI) | Crude odds ratio (95% CI)a | P value | Adjusted odds ratio (95% CI)b | p value | |
|---|---|---|---|---|---|---|---|
| 60–69 | 323 | 52 | 16.1 (12.3–20.6) | Reference | Reference | ||
| 70–79 | 445 | 93 | 20.9 (17.2–25.0) | 1.38 (0.95–2.00) | 0.094 | 1.41 (0.93–2.12) | 0.105 |
| 80 and above | 372 | 125 | 33.6 (28.8–38.7) | 2.64 (1.83–3.80) | < 0.01 | 2.50 (1.64–3.77) | < 0.01 |
| Male | 405 | 72 | 17.8 (14.2–21.8) | Reference | Reference | ||
| Female | 735 | 198 | 26.9 (23.8–30.3) | 1.71 (1.26–2.31) | < 0.01 | 1.48 (0.93–2.34) | 0.094 |
| Higher education | 223 | 31 | 13.9 (9.6–19.1) | Reference | Reference | ||
| School education | 696 | 161 | 23.1 (20.0–26.4) | 1.86 (1.23–2.83) | < 0.01 | 1.35 (0.75–2.45) | 0.321 |
| No schooling | 221 | 78 | 35.3 (29.0–42.0 | 0.30 (0.18–0.47) | < 0.01 | 2.60 (1.31–5.51) | 0.006 |
| Free home | 184 | 39 | 21.2 (15.5–27.8) | Reference | Reference | ||
| Subsidised home | 473 | 122 | 25.8 (21.9–30.0) | 1.29 (0.86–1.95) | 0.22 | 1.60 (1.06–2.57) | 0.051 |
| Paid homes | 483 | 109 | 22.6 (18.9–26.6) | 1.1 (0.71–1.64) | 0.7 | 1.0 (0.61–1.64) | 0.997 |
| Never | 939 | 234 | 24.9 (22.2–27.8) | Reference | Reference | ||
| Past/current | 201 | 36 | 17.9 (12.9–23.9) | 0.66 (0.45–0.97) | 0.035 | 0.97 (0.54–1.70) | 0.923 |
| Never | 935 | 228 | 24.2 (21.7–27.3) | Reference | Reference | ||
| Past/current | 205 | 42 | 20.5 (15.2–26.7) | 0.80 (0.55–1.16) | 0.235 | 1.12 (0.68–1.83) | 0.66 |
| Normal/underweight (< 18.5–25) | 457 | 75 | 16.4 (13.1–20.1) | Reference | Reference | ||
| Overweight (> 25–30) | 310 | 50 | 16.1 (12.2–20.7) | 0.98 (0.66–1.45) | 0.917 | 1.08 (0.71–1.60) | 0.752 |
| Obese (> 30) | 156 | 18 | 11.5 (7.0–17.6) | 0.66 (0.38–1.15) | 0.145 | 0.70 (0.40–1.24) | 0.223 |
| Missing data | 217 | 127 | 58.5 (51.7–65.1) | 7.18 (5.0–10.40) | < 0.01 | 7.54 (5.10–11.17) | < 0.01 |
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aBased on simple logistic regression with multi-morbidity as the outcome variable.
bBased on multiple logistic regression with multi-morbidity as the outcome and all the predictors entered at the same time.
Prevalence of number of non-communicable diseases with 95% confidence intervals.
| Number of participants | Prevalence (95% CI) | |
|---|---|---|
| No disability | 570 | 50.0 (47.1–53.9) |
| One disability | 300 | 26.3 (23.8–29.0) |
| Two disabilities | 153 | 13.4 (11.5–5.5) |
| Three disabilities | 61 | 0.54 (4.1–0.7) |
| Four or more disabilities | 56 | 4.9 (3.7–6.3) |
| Total | 1140 |
Association of at least one assistive device used with sociodemographic characteristics (multiple logistic regression analysis).
| Total in the sample (n) | Participants using at least one assistive device (n) | Prevalence (95% CI) | Adjusted odds ratio (95% CI) | P-value | |
|---|---|---|---|---|---|
| 60–69 | 329 | 191 | 58.1 (52.5–63.4) | Reference | |
| 70–79 | 453 | 327 | 71.2 (67.8–76.3) | 1.83 (1.35–2.49) | < 0.01 |
| 80 and above | 400 | 305 | 76.2 (71.2–8.03) | 2.22 (1.60–3.09) | < 0.01 |
| Male | 418 | 313 | 73.9 (70.4–79.0) | Reference | |
| Female | 764 | 510 | 66.7 (63.3–70.1) | 0.82 (0.61–1.10) | 0.19 |
| No education | 240 | 138 | 57.5 (51.0–63.8) | Reference | |
| School education | 717 | 511 | 71.2 (67.8–74.6) | 1.70 (1.24–2.34) | < 0.01 |
| Higher education | 225 | 174 | 77.3 (71.3–82.6) | 2.14 (1.35–3.38) | < 0.01 |
| Free home | 190 | 109 | 57.3 (50.0–64.50) | Reference | |
| Partially paid/aided | 491 | 347 | 70.7 (66.4–74.7) | 1.41 (0.98–2.02) | 0.07 |
| Completely paid/private homes | 501 | 367 | 73.2 (69.1–77.1) | 1.36 (0.93–1.98) | 0.11 |
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