Literature DB >> 35813841

UNDERSTANDING PREFERENCES FOR TYPE OF TAKE-HOME NALOXONE DEVICE: INTERNATIONAL QUALITATIVE ANALYSIS OF THE VIEWS OF PEOPLE WHO USE OPIOIDS.

Joanne Neale1, Adrian Farrugia2, Aimee N Campbell3, Paul Dietze4, Robyn Dwyer5, Renae Fomiatti2, Jermaine D Jones3, Sandra D Comer3, Suzanne Fraser2, John Strang1.   

Abstract

Background: Take-home naloxone (THN) is provided to non-medically trained people to reverse potential opioid overdoses. There is an increasing range of effective intramuscular (IM) and intranasal (IN) naloxone devices and this paper explores the types preferred by people who use opioids, using consumer behaviour literature to interpret the findings.
Methods: Data derive from two unconnected qualitative studies involving audio-recorded semi-structured interviews. Study 1 was conducted in the United States (n=21 users of non-medical/illicit opioids). Study 2 was conducted in Australia (n=42 users of non-medical/illicit or prescribed opioids). Findings: Most participants preferred IN naloxone. Preferences were based on the ease, speed, safety and comfort of each device and underpinned by accounts of overdose revivals as being very rushed and frightening situations. Preferences related to complex interactions between the naloxone device ('product'); the knowledge, skills, experience and attitudes of the lay responder ('consumer'), and when, where and how naloxone was to be used ('usage situation'). Conclusions: THN programs should offer choice of device when possible and nasal naloxone if resources permit. Asking people which devices they prefer and why and treating them as valued consumers of naloxone products can generate insights that improve future naloxone technology and increase THN uptake and usage.

Entities:  

Keywords:  Consumer behaviour; Iterative Categorization; Naloxone; Overdose; Qualitative; Usage situation

Year:  2021        PMID: 35813841      PMCID: PMC9268211          DOI: 10.1080/09687637.2021.1872499

Source DB:  PubMed          Journal:  Drugs (Abingdon Engl)        ISSN: 0968-7637


  48 in total

Review 1.  Naloxone in opioid poisoning: walking the tightrope.

Authors:  S F J Clarke; P I Dargan; A L Jones
Journal:  Emerg Med J       Date:  2005-09       Impact factor: 2.740

2.  Pharmacokinetics of a new, nasal formulation of naloxone.

Authors:  Ida Tylleskar; Arne Kristian Skulberg; Turid Nilsen; Sissel Skarra; Phatsawee Jansook; Ola Dale
Journal:  Eur J Clin Pharmacol       Date:  2017-01-31       Impact factor: 2.953

Review 3.  Combating Opioid Overdose With Public Access to Naloxone.

Authors:  Kathryn Dambrino Mitchell; Leslie J Higgins
Journal:  J Addict Nurs       Date:  2016 Jul-Sep       Impact factor: 1.476

4.  Perpetuating stigma or reducing risk? Perspectives from naloxone consumers and pharmacists on pharmacy-based naloxone in 2 states.

Authors:  Traci C Green; Patricia Case; Haley Fiske; Janette Baird; Shachan Cabral; Dina Burstein; Victoriana Schwartz; Nathan Potter; Alexander Y Walley; Jeffrey Bratberg
Journal:  J Am Pharm Assoc (2003)       Date:  2017-02-14

Review 5.  Acute heroin overdose.

Authors:  K A Sporer
Journal:  Ann Intern Med       Date:  1999-04-06       Impact factor: 25.391

6.  FDA Initiative for Drug Facts Label for Over-the-Counter Naloxone.

Authors:  Barbara R Cohen; Karen M Mahoney; Elande Baro; Claudia Squire; Melissa Beck; Sara Travis; Amanda Pike-McCrudden; Rima Izem; Janet Woodcock
Journal:  N Engl J Med       Date:  2020-05-28       Impact factor: 91.245

7.  How competent are people who use opioids at responding to overdoses? Qualitative analyses of actions and decisions taken during overdose emergencies.

Authors:  Joanne Neale; Caral Brown; Aimee N C Campbell; Jermaine D Jones; Verena E Metz; John Strang; Sandra D Comer
Journal:  Addiction       Date:  2018-12-28       Impact factor: 6.526

8.  Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose-a randomized controlled trial.

Authors:  Arne Kristian Skulberg; Anders Åsberg; Hasse Zare Khiabani; Hilde Røstad; Ida Tylleskar; Ola Dale
Journal:  Addiction       Date:  2019-02-15       Impact factor: 6.526

9.  Clinical provision of improvised nasal naloxone without experimental testing and without regulatory approval: imaginative shortcut or dangerous bypass of essential safety procedures?

Authors:  John Strang; Rebecca McDonald; Basak Tas; Ed Day
Journal:  Addiction       Date:  2016-02-03       Impact factor: 6.526

Review 10.  Opioid overdose prevention and naloxone rescue kits: what we know and what we don't know.

Authors:  Todd Kerensky; Alexander Y Walley
Journal:  Addict Sci Clin Pract       Date:  2017-01-07
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