Literature DB >> 3579450

Floxacillin-induced cholestatic hepatitis with evidence of lymphocyte sensitization.

R M Victorino, V A Maria, A P Correia, C de Moura.   

Abstract

A severe and prolonged form of biopsy-proved cholestatic hepatitis occurred in a 45-year-old man who had received floxacillin for two weeks preceding the episode of drug-related cholestatic injury. Immunologic tests revealed evidence of in vitro sensitization to the drug as well as to the serum of a normal subject collected after ingestion of floxacillin. Floxacillin should be added to the list of drugs causing cholestatic hepatitis, most likely by an immunologic mechanism.

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Year:  1987        PMID： 3579450

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN： 0003-9926


  6 in total

1.  Risk of cholestatic liver disease associated with flucloxacillin and flucloxacillin prescribing habits in the UK: cohort study using data from the UK General Practice Research Database.

Authors:  Stefan Russmann; James A Kaye; Susan S Jick; Hershel Jick
Journal:  Br J Clin Pharmacol       Date:  2005-07       Impact factor: 4.335

Review 2.  Flucloxacillin associated cholestatic hepatitis. An Australian and Swedish epidemic?

Authors:  B M Devereaux; D H Crawford; P Purcell; L W Powell; H P Roeser
Journal:  Eur J Clin Pharmacol       Date:  1995       Impact factor: 2.953

3.  Diagnostic value of specific T cell reactivity to drugs in 95 cases of drug induced liver injury.

Authors:  V A Maria; R M Victorino
Journal:  Gut       Date:  1997-10       Impact factor: 23.059

4.  Amoxycillin/clavulanic acid (Augmentin)-induced intrahepatic cholestasis.

Authors:  J F Dowsett; T Gillow; A Heagerty; M Radcliffe; R Toadi; I Isle; R C Russell
Journal:  Dig Dis Sci       Date:  1989-08       Impact factor: 3.199

Review 5.  Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Authors:  Patricio Godoy; Nicola J Hewitt; Ute Albrecht; Melvin E Andersen; Nariman Ansari; Sudin Bhattacharya; Johannes Georg Bode; Jennifer Bolleyn; Christoph Borner; Jan Böttger; Albert Braeuning; Robert A Budinsky; Britta Burkhardt; Neil R Cameron; Giovanni Camussi; Chong-Su Cho; Yun-Jaie Choi; J Craig Rowlands; Uta Dahmen; Georg Damm; Olaf Dirsch; María Teresa Donato; Jian Dong; Steven Dooley; Dirk Drasdo; Rowena Eakins; Karine Sá Ferreira; Valentina Fonsato; Joanna Fraczek; Rolf Gebhardt; Andrew Gibson; Matthias Glanemann; Chris E P Goldring; María José Gómez-Lechón; Geny M M Groothuis; Lena Gustavsson; Christelle Guyot; David Hallifax; Seddik Hammad; Adam Hayward; Dieter Häussinger; Claus Hellerbrand; Philip Hewitt; Stefan Hoehme; Hermann-Georg Holzhütter; J Brian Houston; Jens Hrach; Kiyomi Ito; Hartmut Jaeschke; Verena Keitel; Jens M Kelm; B Kevin Park; Claus Kordes; Gerd A Kullak-Ublick; Edward L LeCluyse; Peng Lu; Jennifer Luebke-Wheeler; Anna Lutz; Daniel J Maltman; Madlen Matz-Soja; Patrick McMullen; Irmgard Merfort; Simon Messner; Christoph Meyer; Jessica Mwinyi; Dean J Naisbitt; Andreas K Nussler; Peter Olinga; Francesco Pampaloni; Jingbo Pi; Linda Pluta; Stefan A Przyborski; Anup Ramachandran; Vera Rogiers; Cliff Rowe; Celine Schelcher; Kathrin Schmich; Michael Schwarz; Bijay Singh; Ernst H K Stelzer; Bruno Stieger; Regina Stöber; Yuichi Sugiyama; Ciro Tetta; Wolfgang E Thasler; Tamara Vanhaecke; Mathieu Vinken; Thomas S Weiss; Agata Widera; Courtney G Woods; Jinghai James Xu; Kathy M Yarborough; Jan G Hengstler
Journal:  Arch Toxicol       Date:  2013-08-23       Impact factor: 5.153

6.  Cholestatic hepatitis due to antibacterial combination of amoxicillin and clavulanic acid (augmentin)

Authors:  B H Stricker; J W Van den Broek; J Keuning; W Eberhardt; H G Houben; M Johnson; A P Blok
Journal:  Dig Dis Sci       Date:  1989-10       Impact factor: 3.199
  6 in total

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