Literature DB >> 2752877

Amoxycillin/clavulanic acid (Augmentin)-induced intrahepatic cholestasis.

J F Dowsett1, T Gillow, A Heagerty, M Radcliffe, R Toadi, I Isle, R C Russell.   

Abstract

A 75-year-old man developed a biopsy-proven, drug-induced intrahepatic cholestasis after use of amoxycillin trihydrate combined with the beta-lactam inhibitor potassium clavulanate (Augmentin). Cholestatic liver injury is an uncommonly recognized, probably immunologically based adverse reaction to therapy with penicillin and its derivatives.

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Year:  1989        PMID: 2752877     DOI: 10.1007/bf01537281

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  13 in total

1.  Myocarditis, arteritis, and focal hepatic, splenic, and renal granulomas apparently due to penicillin sensitivity.

Authors:  D WAUGH
Journal:  Am J Pathol       Date:  1952 May-Jun       Impact factor: 4.307

2.  beta-Lactamase inhibitors.

Authors:  C S Conner
Journal:  Drug Intell Clin Pharm       Date:  1985-06

3.  [Hepatotoxicity of drugs. A data bank of hepatic involvement and responsible drugs].

Authors:  M Biour; R Poupon; Y Calmus; J D Grange; J Jablonka; V G Levy; F Darnis; G Cheymol
Journal:  Gastroenterol Clin Biol       Date:  1987-01

4.  Cholestatic jaundice due to derivatives of oxacillin.

Authors:  G Deboever
Journal:  Am J Gastroenterol       Date:  1987-05       Impact factor: 10.864

5.  Severe penicillin-induced cholestasis in a 91-year-old woman.

Authors:  C N Williams; D A Malatjalian
Journal:  Dig Dis Sci       Date:  1981-05       Impact factor: 3.199

Review 6.  Beta-lactamase inhibitors: another approach to overcoming antimicrobial resistance.

Authors:  R H Parker; M Eggleston
Journal:  Infect Control       Date:  1987-01

7.  Treatment of respiratory tract infections with a combination of amoxycillin and clavulanic acid.

Authors:  G N Karachalios
Journal:  Int J Clin Pharmacol Ther Toxicol       Date:  1985-12

8.  Flucloxacillin-induced cholestatic liver damage.

Authors:  F Bengtsson; C H Florén; I Hägerstrand; C Söderström; T Aberg
Journal:  Scand J Infect Dis       Date:  1985

9.  Cloxacillin-induced cholestatic jaundice.

Authors:  F Konikoff; J Alcalay; J Halevy
Journal:  Am J Gastroenterol       Date:  1986-11       Impact factor: 10.864

10.  Cholestatic jaundice caused by cloxacillin: macrophage inhibition factor test in preventing rechallenge with hepatotoxic drugs.

Authors:  R Enat; S Pollack; Y Ben-Arieh; E Livni; D Barzilai
Journal:  Br Med J       Date:  1980-04-05
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  4 in total

1.  Hepatitis and augmentin.

Authors:  K R Reddy; E R Schiff
Journal:  Dig Dis Sci       Date:  1990-08       Impact factor: 3.199

2.  Granulomatous hepatitis due to combination of amoxicillin and clavulanic acid.

Authors:  C Silvain; E Fort; P Levillain; J Labat-Labourdette; M Beauchant
Journal:  Dig Dis Sci       Date:  1992-01       Impact factor: 3.199

Review 3.  Drug-induced "allergic hepatitis".

Authors:  P Podevin; M Biour
Journal:  Clin Rev Allergy Immunol       Date:  1995       Impact factor: 8.667

4.  Hepatitis associated with amoxycillin-clavulanic acid combination report of 15 cases.

Authors:  D Larrey; T Vial; A Micaleff; G Babany; M Morichau-Beauchant; H Michel; J P Benhamou
Journal:  Gut       Date:  1992-03       Impact factor: 23.059

  4 in total

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