Literature DB >> 35782808

Modified Radical Mastectomy vs Breast-Conserving Surgery: Current Clinical Practice in Women with Early Stage Breast Cancer at a Corporate Tertiary Cancer Center in India.

Sachin S Kadam1, Pradeep Tripathi2, Rohan Jagtap3, Rajat Kapoor4, Tejaswini Kadam5, Prashant Bhandarkar6, Sakshi Shimpi6.   

Abstract

Breast cancer is the most common cancer in women in urban India and surgery has one of the definitive roles in treating this cancer. Over the decades, multiple studies have been published and they have shown that BCS followed by radiotherapy has equivalent disease-free survival (DFS) and overall survival (OS) as compared with MRM. The surgeon has the main role in explaining the treatment options to the patient. It is a prospective study conducted at Vedant Cancer and Multispeciality Hospital in a metropolitan city, Thane, India. Patients with stage I or II breast cancer with tumor size less than 5 cm were included in the study. Patients with locally advanced and metastatic breast cancer were excluded from the study. The study population was early breast cancer patients registered and waiting for surgery (n = 86) at Vedant Cancer and Multispeciality Hospital from November 2019 to end of April 2020. The total number of females enrolled in the study were 86 and out of this, 79.1% (n = 68) females opted for MRM and 20.9% (n = 18) females opted for BCS in which 8 patients had changed their decision after re-counseling in the ward from MRM to BCS. The most common reasons selected by patients to undergo MRM were fear of cancer recurrence (30.2%, n = 26), avoidance of side effects of radiation therapy (25.5%, n = 22) and fear of radiation therapy (23.2%, n = 20). Surgeon had decided the surgical option in 79.1% (n = 68) cases. The study shows that the treating surgeon and patient's husband are the principal persons who decide the surgical option and active participation of women during counseling is an important factor. Supplementary Information: The online version contains supplementary material available at 10.1007/s13193-021-01457-8. © Indian Association of Surgical Oncology 2021.

Entities:  

Keywords:  BCS; Counseling; Early breast cancer; MRM; Patient participation

Year:  2021        PMID: 35782808      PMCID: PMC9240152          DOI: 10.1007/s13193-021-01457-8

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  20 in total

1.  Patient involvement in surgery treatment decisions for breast cancer.

Authors:  Steven J Katz; Paula M Lantz; Nancy K Janz; Angela Fagerlin; Kendra Schwartz; Lihua Liu; Dennis Deapen; Barbara Salem; Indu Lakhani; Monica Morrow
Journal:  J Clin Oncol       Date:  2005-08-20       Impact factor: 44.544

Review 2.  Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials.

Authors:  M Clarke; R Collins; S Darby; C Davies; P Elphinstone; V Evans; J Godwin; R Gray; C Hicks; S James; E MacKinnon; P McGale; T McHugh; R Peto; C Taylor; Y Wang
Journal:  Lancet       Date:  2005-12-17       Impact factor: 79.321

3.  Measuring and predicting surgeons' practice styles for breast cancer treatment in older women.

Authors:  J S Mandelblatt; C D Berg; N J Meropol; S B Edge; K Gold; Y T Hwang; J Hadley
Journal:  Med Care       Date:  2001-03       Impact factor: 2.983

4.  Disparities in the Use of Breast-Conserving Therapy Among Patients With Early-Stage Breast Cancer.

Authors:  Meeghan Lautner; Heather Lin; Yu Shen; Catherine Parker; Henry Kuerer; Simona Shaitelman; Gildy Babiera; Isabelle Bedrosian
Journal:  JAMA Surg       Date:  2015-08       Impact factor: 14.766

5.  Determinants of choice of surgery in Asian patients with early breast cancer in a middle income country.

Authors:  Yew-Ching Teh; Nor Elina Noor Shaari; Nur Aishah Taib; Char-Hong Ng; Mee-Hoong See; Gie-Hooi Tan; Suniza Jamaris; Cheng-Har Yip
Journal:  Asian Pac J Cancer Prev       Date:  2014

6.  Determinants of breast conservation rates: reasons for mastectomy at a comprehensive cancer center.

Authors:  M Catherine Lee; Kendra Rogers; Kent Griffith; Kathleen A Diehl; Tara M Breslin; Vincent M Cimmino; Alfred E Chang; Lisa A Newman; Michael S Sabel
Journal:  Breast J       Date:  2009 Jan-Feb       Impact factor: 2.431

7.  Surgeon characteristics and use of breast conservation surgery in women with early stage breast cancer.

Authors:  Dawn L Hershman; Donna Buono; Judith S Jacobson; Russell B McBride; Wei Yann Tsai; Kathie Ann Joseph; Alfred I Neugut
Journal:  Ann Surg       Date:  2009-05       Impact factor: 12.969

Review 8.  Statutory requirements for disclosure of breast cancer treatment alternatives.

Authors:  S G Nayfield; G C Bongiovanni; M H Alciati; R A Fischer; L Bergner
Journal:  J Natl Cancer Inst       Date:  1994-08-17       Impact factor: 13.506

9.  Fear of recurrence and perceived survival benefit are primary motivators for choosing mastectomy over breast-conservation therapy regardless of age.

Authors:  Carla S Fisher; Tonya Martin-Dunlap; Megan Baker Ruppel; Feng Gao; Jordan Atkins; Julie A Margenthaler
Journal:  Ann Surg Oncol       Date:  2012-07-26       Impact factor: 5.344

10.  Factors associated with health-related quality-of-life in breast cancer survivors: influence of the type of surgery.

Authors:  Shozo Ohsumi; Kojiro Shimozuma; Satoshi Morita; Fumikata Hara; Daisuke Takabatake; Seiki Takashima; Naruto Taira; Kenjiro Aogi; Shigemitsu Takashima
Journal:  Jpn J Clin Oncol       Date:  2009-06-11       Impact factor: 3.019

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