Literature DB >> 35775275

A Folk Medicine: Passiflora incarnata L. Phytochemical Profile with Antioxidant Potency.

Helan Soundra Rani Michael1, Nazneen Bobby Mohammed2, Subramaniam Ponnusamy3, Wesely Edward Gnanaraj3.   

Abstract

Objectives: Passiflora incarnata L., commonly called folk medicine declaredly used for an enormous range of therapeutic purposes, one such is antioxidant potency. The study prioritized to determine the phytochemical analysis of total phenolics, flavonoids, alkaloids, and tannins contents as well as the antioxidant properties through 1,1-diphenyl-2-picrylhydrazyl (DPPH) quenching assay, 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) cation decolorization test, superoxide, and hydrogen peroxide radical scavenging assays of ethanol extract of P. incarnata leaves. Materials and
Methods: The organoleptic characteristics such as color, odor, appearance, taste, and other characters such as drying range and fiber contents were analyzed as preliminary data. Analytical parameters like total phenolic content, total tannins, total alkaloid content, and total flavonoid with multiple antiradical scavenging activity (DPPH, ABTS, superoxide and H2O2 scavenging assays) with IC50 (μg/mL) in terms of inhibition percentage with various concentrations of the ethanolic extract studied.
Results: P. incarnata possessed a high radical scavenging activity with a phenolic content of 2.48 mg gallic acid equivalent/g of extract in leaves, whereas the total flavonoid content was 2.1, respectively.
Conclusion: High antioxidant activity was noticed in P. incarnata extract, in which might be of higher levels of flavonoids and phenols. Findings in the studies revealed that P. incarnata is a veritable source for antioxidant drug bioprospecting in scientific research and pharmaceutical industries. ©Turk J Pharm Sci, Published by Galenos Publishing House.

Entities:  

Keywords:  ABTS; DPPH; Passiflora incarnata; antioxidant activity; phytochemical profile; radical scavenging activity

Year:  2022        PMID: 35775275      PMCID: PMC9254093          DOI: 10.4274/tjps.galenos.2021.88886

Source DB:  PubMed          Journal:  Turk J Pharm Sci        ISSN: 1304-530X


  14 in total

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2.  Comparison of the total phenolic and ascorbic acid content of freeze-dried and air-dried marionberry, strawberry, and corn grown using conventional, organic, and sustainable agricultural practices.

Authors:  Danny K Asami; Yun-Jeong Hong; Diane M Barrett; Alyson E Mitchell
Journal:  J Agric Food Chem       Date:  2003-02-26       Impact factor: 5.279

3.  Phenolic compound profiles and their corresponding antioxidant Capacity of purple pitaya (Hylocereus sp.) genotypes.

Authors:  Patricia Esquivel; Florian C Stintzing; Reinhold Carle
Journal:  Z Naturforsch C J Biosci       Date:  2007 Sep-Oct

4.  Pharmacognosy and chemotypes of passionflower (Passiflora incarnata L.).

Authors:  Hans Wohlmuth; Kerry George Penman; Tanya Pearson; Reginald Paul Lehmann
Journal:  Biol Pharm Bull       Date:  2010       Impact factor: 2.233

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Review 6.  Lipid peroxidation-DNA damage by malondialdehyde.

Authors:  L J Marnett
Journal:  Mutat Res       Date:  1999-03-08       Impact factor: 2.433

7.  Phenolic compounds and an analog as superoxide anion scavengers and antioxidants.

Authors:  Y C Zhou; R L Zheng
Journal:  Biochem Pharmacol       Date:  1991-08-22       Impact factor: 5.858

Review 8.  Role of oxidant species in aging.

Authors:  Earl R Stadtman
Journal:  Curr Med Chem       Date:  2004-05       Impact factor: 4.530

9.  Antioxidant activities of extracts and fractions from Lysimachia foenum-graecum Hance.

Authors:  Hai-yun Li; Zai-bin Hao; Xiu-li Wang; Lei Huang; Jian-ping Li
Journal:  Bioresour Technol       Date:  2008-09-14       Impact factor: 9.642

10.  Correct Identification of Passiflora incarnata Linn., a Promising Herbal Anxiolytic and Sedative.

Authors:  Kamaldeep Dhawan; Rajesh Kumar; Suresh Kumar; Anupam Sharma
Journal:  J Med Food       Date:  2001       Impact factor: 2.786

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