Literature DB >> 35774928

The eradication rate of infection in septic knee arthritis according to the Gächter Classification: a systematic review.

Cristiano De Franco1, Stefano Artiaco2, Vincenzo de Matteo1, Alessandro Bistolfi2, Giovanni Balato1, Salvatore Vallefuoco1, Alessandro Massè2, Donato Rosa1.   

Abstract

Introduction: Knee septic arthritis rapidly damages the knee joint. Gächter described a classification of joint infections based on arthroscopic findings: an arthroscopic staging of the common disease has prognostic and therapeutic consequences. The aim of this systematic review was to analyze the application of the Gächter classification system to knee septic arthritis, evaluating prognostic and therapeutic implications of this classification. Materials and
Methods: A comprehensive electronic search of the literature was performed. The following search terms were used: (Arthroscopy* OR Arthrotom* OR Aspiration) AND Knee AND Septic AND Arthritis. The study reported the Gächter classification in septic knee arthritis and the eradication rate according to the type. The primary endpoint is the eradication rate of septic knee arthritis according to the Gächter sort. Secondary endpoints are surgical procedures according to Gächter classification and the rate of re-operations.
Results: Seven studies were included. The overall eradication rate of knee septic arthritis ranged from 90% to 100%: 95%-100% Gächter I; 97%-100% Gächter II; 67%-100% Gächter III; 50%-100% Gächter IV. Surgical treatments for knee septic arthritis included arthroscopic irrigation alone, articular irrigation, and debridement in knee arthroscopy or knee arthrotomy according to Gächter stage. However, 28% required re-operations for persistent infection: secondary procedures included further irrigation and debridement with the arthroscopic or arthrotomic approach.
Conclusion: Gächter classification showed a crucial prognostic role in predicting the outcome of surgical treatment of septic knee arthritis. Regardless of the procedure performed, a prompt operation and an accurate debridement of the synovial membrane are the most critical factors for eradicating infection and good clinical outcomes. Level of Evidence: Level II, prognostic study.

Entities:  

Keywords:  Gächter classification; arthroscopic debridement; debridement; knee septic arthritis; open debridement.

Year:  2022        PMID: 35774928      PMCID: PMC9239385          DOI: 10.52965/001c.33754

Source DB:  PubMed          Journal:  Orthop Rev (Pavia)        ISSN: 2035-8164


  28 in total

1.  Microbiological profile of septic arthritis in adults: Lessons learnt and treatment strategies.

Authors:  Jerry George; V J Chandy; John Premnath; T D Hariharan; Anil Thomas Oommen; V Balaji; Pradeep M Poonnoose
Journal:  Indian J Med Microbiol       Date:  2019 Jan-Mar       Impact factor: 0.985

2.  The relation between the arthroscopic findings and functional outcomes in patients with septic arthritis of the knee joint, treated with arthroscopic debridement and irrigation.

Authors:  Ibrahim Yanmış; Hüseyin Ozkan; Kenan Koca; Volkan Kılınçoğlu; Doğan Bek; Servet Tunay
Journal:  Acta Orthop Traumatol Turc       Date:  2011       Impact factor: 1.511

3.  Efficacy of arthroscopic treatment for resolving infection in septic arthritis of native joints.

Authors:  F Aïm; J Delambre; T Bauer; P Hardy
Journal:  Orthop Traumatol Surg Res       Date:  2015-01-23       Impact factor: 2.256

4.  Septic Arthritis of Native Shoulder and Knee Joint: What Are the Differences in Bacterial Spectrum, Treatment, and Outcome?

Authors:  Yves Gramlich; Alexander Klug; Gerhard Walter; Michael Kremer; Reinhard Hoffmann; Matthias Kemmerer
Journal:  Surg Infect (Larchmt)       Date:  2019-12-16       Impact factor: 2.150

5.  Bacterial Septic Arthritis of the Adult Native Knee Joint: A Review.

Authors:  Joseph G Elsissy; Joseph N Liu; Peter J Wilton; Ikenna Nwachuku; Anirudh K Gowd; Nirav H Amin
Journal:  JBJS Rev       Date:  2020-01

Review 6.  Approach to septic arthritis.

Authors:  Diane Lewis Horowitz; Elena Katzap; Scott Horowitz; Maria-Louise Barilla-LaBarca
Journal:  Am Fam Physician       Date:  2011-09-15       Impact factor: 3.292

Review 7.  Peripheral Bacterial Septic Arthritis: Review of Diagnosis and Management.

Authors:  Ahmed S Hassan; Allison Rao; Augustine M Manadan; Joel A Block
Journal:  J Clin Rheumatol       Date:  2017-12       Impact factor: 3.517

8.  Prevention and treatment of peri-prosthetic joint infection using surgical wound irrigation.

Authors:  G Balato; V De Matteo; C De Franco; M Lenzi; R Verrazzo; R de Giovanni; F Smeraglia; M Rizzo; T Ascione
Journal:  J Biol Regul Homeost Agents       Date:  2020 Sep-Oct       Impact factor: 1.711

9.  Septic arthritis of the knee in adults: treatment by arthroscopy or arthrotomy.

Authors:  D C Wirtz; M Marth; O Miltner; U Schneider; K W Zilkens
Journal:  Int Orthop       Date:  2001       Impact factor: 3.075

10.  Epidemiology of septic arthritis of the knee at Hospital das Clínicas, Universidade de São Paulo.

Authors:  Camilo Partezani Helito; Guilherme Guelfi Noffs; Jose Ricardo Pecora; Riccardo Gomes Gobbi; Luis Eduardo Passarelli Tirico; Ana Lucia Munhoz Lima; Priscila Rosalba de Oliveira; Gilberto Luis Camanho
Journal:  Braz J Infect Dis       Date:  2013-09-09       Impact factor: 3.257

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