Literature DB >> 35774669

Bilateral Papilledema and Right Esotropia as an Initial Presentation of Acute Myeloid Leukemia in a Young Girl.

Reem M Hersi1, Ayat M Aldosari2, Nada K Naaman1, Rawan K Alrajhi1, Abdullah S Alqahtani3.   

Abstract

Leukemia is a malignant hematologic neoplastic disease in which acquired mutations and genetic abnormalities in early hematopoietic precursors cause rapid proliferation of white blood cells (WBC). Acute myeloid leukemia (AML), a subtype of leukemia, is a rare form of cancer that typically manifests in adulthood. Symptoms typically arise due to abnormal proliferation of WBC. Ocular manifestations of such malignancies are rare and they occur more commonly in acute lymphoblastic leukemia (ALL) rather than AML. Furthermore, ophthalmic involvement usually is either a sign of central nervous system involvement or disease relapse. In this article, we report the case of a 14-year-old girl who presented initially with double vision and right eye squint. The patient was later diagnosed with AML with leptomeningeal involvement.
Copyright © 2022, Hersi et al.

Entities:  

Keywords:  anemia; esotropia; intracranial pressure; leukemia; papilledema; pediatric oncology

Year:  2022        PMID: 35774669      PMCID: PMC9236691          DOI: 10.7759/cureus.25413

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  19 in total

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Journal:  Blood       Date:  1997-07-15       Impact factor: 22.113

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4.  Ophthalmic Manifestations in Acute Leukemia Patients and Their Relation With Hematological Parameters in a Tertiary Care Center.

Authors:  Ziad M Bukhari; Abdulmalek Alzahrani; Mohammed S Alqarni; Rakan S Alajmi; Ali Alzahrani; Hashim Almarzouki; Abdullah S Alqahtani
Journal:  Cureus       Date:  2021-11-08

5.  Ophthalmic manifestations of leukemia in a tertiary hospital population of adult nigerian africans.

Authors:  Boniface I Eze; Godswill O Ibegbulam; Sunday Ocheni
Journal:  Middle East Afr J Ophthalmol       Date:  2010-10

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Authors:  S C Reddy; N Jackson; B S Menon
Journal:  Ophthalmologica       Date:  2003 Nov-Dec       Impact factor: 3.250

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Authors:  J W Karesh; E J Goldman; K Reck; S E Kelman; E J Lee; C A Schiffer
Journal:  J Clin Oncol       Date:  1989-10       Impact factor: 44.544

8.  Acute Myeloid Leukemia: A Review.

Authors:  Ari Pelcovits; Rabin Niroula
Journal:  R I Med J (2013)       Date:  2020-04-01

9.  A Case of Acute Promyelocytic Leukemia With Retinal Hemorrhages Beneath Internal Limiting Membrane During Clinical Remission.

Authors:  Marwan M Balubaid; Abdullah S Alqahtani
Journal:  Cureus       Date:  2021-02-17
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