Literature DB >> 35756858

Obesity Prediction with EHR Data: A deep learning approach with interpretable elements.

Mehak Gupta1, Thao-Ly T Phan2, H Timothy Bunnell2, Rahmatollah Beheshti1.   

Abstract

Childhood obesity is a major public health challenge. Early prediction and identification of the children at an elevated risk of developing childhood obesity may help in engaging earlier and more effective interventions to prevent and manage obesity. Most existing predictive tools for childhood obesity primarily rely on traditional regression-type methods using only a few hand-picked features and without exploiting longitudinal patterns of children's data. Deep learning methods allow the use of high-dimensional longitudinal datasets. In this paper, we present a deep learning model designed for predicting future obesity patterns from generally available items on children's medical history. To do this, we use a large unaugmented electronic health records dataset from a large pediatric health system in the US. We adopt a general LSTM network architecture and train our proposed model using both static and dynamic EHR data. To add interpretability, we have additionally included an attention layer to calculate the attention scores for the timestamps and rank features of each timestamp. Our model is used to predict obesity for ages between 3-20 years using the data from 1-3 years in advance. We compare the performance of our LSTM model with a series of existing studies in the literature and show it outperforms their performance in most age ranges.

Entities:  

Keywords:  Applied computing; Childhood obesity; Computing methodologies; Deep learning; Electronic health records; Health informatics; Long short-term memory; Neural networks; Temporal data; Transfer learning

Year:  2022        PMID: 35756858      PMCID: PMC9221869          DOI: 10.1145/3506719

Source DB:  PubMed          Journal:  ACM Trans Comput Healthc        ISSN: 2637-8051


  52 in total

Review 1.  Obesity hypoventilation syndrome: a state-of-the-art review.

Authors:  Babak Mokhlesi
Journal:  Respir Care       Date:  2010-10       Impact factor: 2.258

2.  Infant weight gain and childhood overweight status in a multicenter, cohort study.

Authors:  Nicolas Stettler; Babette S Zemel; Shiriki Kumanyika; Virginia A Stallings
Journal:  Pediatrics       Date:  2002-02       Impact factor: 7.124

3.  Obesity in achondroplasia.

Authors:  J T Hecht; O J Hood; R J Schwartz; J C Hennessey; B A Bernhardt; W A Horton
Journal:  Am J Med Genet       Date:  1988-11

Review 4.  Interventions to prevent global childhood overweight and obesity: a systematic review.

Authors:  Sara N Bleich; Kelsey A Vercammen; Laura Y Zatz; Johannah M Frelier; Cara B Ebbeling; Anna Peeters
Journal:  Lancet Diabetes Endocrinol       Date:  2017-10-20       Impact factor: 32.069

5.  Utility and applicability of the "Childhood Obesity Risk Evaluation" (CORE)-index in predicting obesity in childhood and adolescence in Greece from early life: the "National Action Plan for Public Health".

Authors:  Yannis Manios; Elpis Vlachopapadopoulou; George Moschonis; Feneli Karachaliou; Theodora Psaltopoulou; Dimitra Koutsouki; Gregory Bogdanis; Vilelmine Carayanni; Angelos Hatzakis; Stefanos Michalacos
Journal:  Eur J Pediatr       Date:  2016-10-29       Impact factor: 3.183

Review 6.  Health consequences of obesity in youth: childhood predictors of adult disease.

Authors:  W H Dietz
Journal:  Pediatrics       Date:  1998-03       Impact factor: 7.124

7.  Obesity is associated with sensorineural hearing loss in adolescents.

Authors:  Anil K Lalwani; Karin Katz; Ying-Hua Liu; Sarah Kim; Michael Weitzman
Journal:  Laryngoscope       Date:  2013-06-17       Impact factor: 3.325

Review 8.  Rapid infancy weight gain and subsequent obesity: systematic reviews and hopeful suggestions.

Authors:  Ken K Ong; Ruth J F Loos
Journal:  Acta Paediatr       Date:  2006-08       Impact factor: 2.299

9.  Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts.

Authors:  Anita Morandi; David Meyre; Stéphane Lobbens; Ken Kleinman; Marika Kaakinen; Sheryl L Rifas-Shiman; Vincent Vatin; Stefan Gaget; Anneli Pouta; Anna-Liisa Hartikainen; Jaana Laitinen; Aimo Ruokonen; Shikta Das; Anokhi Ali Khan; Paul Elliott; Claudio Maffeis; Matthew W Gillman; Marjo-Riitta Järvelin; Philippe Froguel
Journal:  PLoS One       Date:  2012-11-28       Impact factor: 3.240

10.  Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus.

Authors:  Z Pei; C Flexeder; E Fuertes; E Thiering; B Koletzko; C Cramer; D Berdel; I Lehmann; C-P Bauer; J Heinrich
Journal:  Eur J Clin Nutr       Date:  2013-04-24       Impact factor: 4.016

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  1 in total

1.  Obesity Prediction with EHR Data: A deep learning approach with interpretable elements.

Authors:  Mehak Gupta; Thao-Ly T Phan; H Timothy Bunnell; Rahmatollah Beheshti
Journal:  ACM Trans Comput Healthc       Date:  2022-04-07
  1 in total

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